Tiruneh Yordanos M, Wilson Ira B
Department of Health Services, Policy & Practice, Brown University, Providence, RI, USA.
Center for Gerontology and Health Care Research, Brown University School of Public Health, Box G-S121-6, Providence, RI, 02912, USA.
AIDS Behav. 2016 Nov;20(11):2662-2673. doi: 10.1007/s10461-016-1322-0.
This study assessed adherence to antiretroviral therapy (ART) among people living with HIV/AIDS in Ethiopia and explored the sociocultural context in which they relate to their regimen requirements. Data were collected through semi-structured in-depth interviews with 105 patients on ART and observations held at the study clinic. We analyzed data using both qualitative and quantitative methods. Our findings indicate that study participants are highly adherent to dose but less adherent to dose schedule. Strict dose time instructions were reported as stressful and unrealistic. The discrepancy between adherence to dose and dose schedule could be explained by time perception, difficulty with the strictness of medication regimens, or beliefs about dose timing adherence. Care providers should acknowledge the complexities of medication practices and engage in shared decision-making to incorporate patients' perspectives and identify effective interventions.
本研究评估了埃塞俄比亚艾滋病毒/艾滋病感染者对抗逆转录病毒疗法(ART)的依从性,并探讨了他们与治疗方案要求相关的社会文化背景。通过对105名接受抗逆转录病毒治疗的患者进行半结构化深度访谈以及在研究诊所进行观察来收集数据。我们使用定性和定量方法对数据进行了分析。我们的研究结果表明,研究参与者对剂量的依从性较高,但对服药时间安排的依从性较低。据报告,严格的服药时间指示压力大且不现实。对剂量和服药时间安排的依从性差异可以通过时间观念、药物治疗方案严格性带来的困难或对服药时间依从性的信念来解释。医护人员应认识到用药实践的复杂性,并参与共同决策,以纳入患者的观点并确定有效的干预措施。