Ishida M, Hosokawa M, Genba K, Daikuhara H, Ishihama H, Ishida Y, Inada T, Kageyama H, Tsuruno M, Tsumura M
Dept. of Int. Med., Kagawa Rosai Hospital.
Gan No Rinsho. 1989 Nov;35(14):1687-92.
A case of a gastric carcinoid tumor with a coexisting adenocarcinoma in the same tumor is reported. The patient was a 71-year-old man who complained of epigastralgia. His physical examination and routine laboratory data were unremarkable. An upper GI x-ray series and the gastroendoscopic findings, however, demonstrated a Borrmann 2-like tumor of the antrum. An endoscopic biopsy specimen from the tumor revealed that it was a gastric adenocarcinoma. Therefore, a subtotal gastrectomy with a lymph node dissection was performed. The resected specimen showed a Borrmann 2-like tumor, but also that infiltration was limited to within the submucosal layer. The pathological findings revealed that the tumor contained two differential component structures (a carcinoid and an adenocarcinoma). The carcinoid and adenocarcinoma structures coexisted with transitional changes that connected both structures. Pathohistologically, it was thought that these two differential components developed from a common origin.
本文报告一例胃类癌肿瘤与同一肿瘤内并存腺癌的病例。患者为一名71岁男性,主诉上腹部疼痛。其体格检查和常规实验室检查数据均无异常。然而,上消化道X线系列检查和胃镜检查结果显示胃窦部有类似Borrmann 2型的肿瘤。肿瘤的内镜活检标本显示为胃腺癌。因此,行胃次全切除术并进行淋巴结清扫。切除标本显示为类似Borrmann 2型的肿瘤,但浸润仅限于黏膜下层。病理检查结果显示肿瘤包含两种不同的成分结构(类癌和腺癌)。类癌和腺癌结构并存,并伴有连接两者的过渡性变化。病理组织学认为,这两种不同的成分起源于共同的来源。