Bao Yanyan, Gao Yingjie, Cui Xiaolan
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences.
Biosci Trends. 2016 Feb;10(1):74-8. doi: 10.5582/bst.2015.01172. Epub 2016 Feb 15.
This study sought to investigate the broad-spectrum antibacterial action of an alternative medicine, Shufeng Jiedu capsules (SFJDC). Antibacterial testing was performed to determine whether SFJDC had broad-spectrum antibacterial action in vitro, and testing was performed to verify whether SFJDC prevented death due to a Streptococcus or Staphylococcus aureus infection in mice. Results of antibacterial testing suggested that SFJDC are a broad-spectrum antibacterial and that SFJDC are superior to Lianhua Qingwen capsules as a broad-spectrum antibacterial. Results of testing revealed that SFJDC lowered the mortality rate, it reduced mortality, it increased average survival time, and it increased the lifespan of mice dying due to a Staphylococcus aureus or Streptococcus infection. Thus, SFJDC could become a complement to broad-spectrum antimicrobials in clinical settings.
本研究旨在探究一种替代药物——疏风解毒胶囊(SFJDC)的广谱抗菌作用。进行了抗菌测试以确定SFJDC在体外是否具有广谱抗菌作用,并进行了测试以验证SFJDC是否能预防小鼠因感染链球菌或金黄色葡萄球菌而死亡。抗菌测试结果表明,SFJDC具有广谱抗菌作用,且作为广谱抗菌药物,SFJDC优于连花清瘟胶囊。测试结果显示,SFJDC降低了死亡率,减少了死亡数量,增加了平均存活时间,并延长了因金黄色葡萄球菌或链球菌感染而死亡的小鼠的寿命。因此,SFJDC可成为临床环境中广谱抗菌药物的一种补充。