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中医药防治新冠肺炎。

Traditional Chinese Medicine as the Preventive and Therapeutic Remedy for COVID-19.

机构信息

Société Francophone de Nutrithérapie et de Nutrigénétique Appliquée, Villeurbanne, France.

Nutritional and Environmental Section, Thailand Initiatives for Functional Medicine, Bangkok, Thailand.

出版信息

Curr Med Chem. 2024;31(21):3118-3131. doi: 10.2174/0929867330666230331084126.


DOI:10.2174/0929867330666230331084126
PMID:36999715
Abstract

The coronavirus disease 2019 (COVID-19) pandemic still has tremendous impacts on the global socio-economy and quality of living. The traditional Chinese Medicines (TCM) approach showed encouraging results during previous outbreaks of Severe Acute Respiratory Syndrome-related Coronavirus (SARS-CoV) and the Middle East Respiratory Syndrome Coronavirus (MERS-CoV). With limited treatment availability, TCM herbs and formulations could be useful to reduce COVID-19 symptoms and potential sources for discovering novel therapeutic targets. We reviewed 12 TCM herbs and formulations recommended for COVID-19 management by the National Health Commission and as National Administration of Traditional Chinese Medicine of the People's Republic of China. This article explored the Chinese national authorities' guidelines from 2003 to 2020, the scientific data in public databases for the recommended TCM remedies, and their potential mechanistic actions in COVID-19 management. Several TCM herbs and formulations could potentially benefit COVID-19 management. The recommended TCM oral preparations list includes , and ; the recommended injection preparations comprise Xiyanping , and . TCM remedies are viable options for symptom alleviation and management of COVID-19. The current SARS-CoV-2 pandemic presents an opportunity to find novel therapeutic targets from TCM-active ingredients. Despite the recommendations in Chinese National guidelines, these remedies warrant further assessments in well-designed clinical trials to ascertain their efficacy in the treatment of COVID-19.

摘要

2019 年冠状病毒病(COVID-19)大流行仍对全球社会经济和生活质量产生巨大影响。传统中药(TCM)在以前的严重急性呼吸系统综合征相关冠状病毒(SARS-CoV)和中东呼吸系统综合征冠状病毒(MERS-CoV)爆发期间显示出令人鼓舞的结果。由于治疗方法有限,TCM 草药和配方可能有助于减轻 COVID-19 症状,并为发现新的治疗靶点提供潜在来源。我们回顾了国家卫生健康委员会和中华人民共和国国家中医药管理局推荐用于 COVID-19 管理的 12 种 TCM 草药和配方。本文探讨了中国国家当局 2003 年至 2020 年的指南、公共数据库中推荐的 TCM 补救措施的科学数据,以及它们在 COVID-19 管理中的潜在机制作用。几种 TCM 草药和配方可能对 COVID-19 管理有益。推荐的 TCM 口服制剂包括连花清瘟胶囊、金花清感颗粒、疏风解毒胶囊;推荐的注射制剂包括喜炎平注射液、血必净注射液。TCM 补救措施是缓解 COVID-19 症状和管理的可行选择。目前的 SARS-CoV-2 大流行为从 TCM 活性成分中寻找新的治疗靶点提供了机会。尽管中国国家指南有这些建议,但这些补救措施仍需要在精心设计的临床试验中进行进一步评估,以确定它们在 COVID-19 治疗中的疗效。

相似文献

[1]
Traditional Chinese Medicine as the Preventive and Therapeutic Remedy for COVID-19.

Curr Med Chem. 2024

[2]
[Analysis on clinical study protocols of traditional Chinese medicine for coronavirus disease 2019].

Zhongguo Zhong Yao Za Zhi. 2020-3

[3]
[Research progress of intervention of Chinese herbal medicine and its active components on human coronavirus].

Zhongguo Zhong Yao Za Zhi. 2020-3

[4]
Traditional Chinese medicine for treatment of novel infectious diseases: Current status and dilemma.

Biosci Trends. 2021-9-22

[5]
Efficacy of Huoxiang Zhengqi dropping pills and Lianhua Qingwen granules in treatment of COVID-19: A randomized controlled trial.

Pharmacol Res. 2020-8-8

[6]
Traditional Chinese Medicine as a complementary therapy in combat with COVID-19-A review of evidence-based research and clinical practice.

J Adv Nurs. 2021-4

[7]
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Curr Pharm Des. 2024

[8]
Traditional Chinese medicine to treat COVID-19: the importance of evidence-based research.

Drug Discov Ther. 2020

[9]
Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis.

Phytomedicine. 2020-9-28

[10]
Traditional Chinese Medicine (TCM) in the treatment of COVID-19 and other viral infections: Efficacies and mechanisms.

Pharmacol Ther. 2021-9

引用本文的文献

[1]
Exploring the pathogenesis of acute lung injury and its treatment through Traditional Chinese Medicine: a state-of-the-art review.

Front Pharmacol. 2025-7-31

[2]
Effectiveness of seven oral traditional Chinese medicines against mild or moderate COVID-19: An updated systematic review and network meta-analysis.

Heliyon. 2024-7-24

[3]
Ayurvedic and Chinese Herbs against Coronaviruses.

Curr Pharm Des. 2024

本文引用的文献

[1]
Traditional Chinese Medicine in Treatment of COVID-19 and Viral Disease: Efficacies and Clinical Evidence.

Int J Gen Med. 2022-11-28

[2]
Addendum: The efficacy and safety of Favipiravir in treatment of COVID-19: a systematic review and meta-analysis of clinical trials.

Sci Rep. 2022-2-1

[3]
Omicron variant of SARS-CoV-2: Genomics, transmissibility, and responses to current COVID-19 vaccines.

J Med Virol. 2022-5

[4]
Analysis on oral medication rules of traditional Chinese medicine prescriptions for prevention of COVID-19.

Chin Herb Med. 2021-10

[5]
Chinese herbal injections for coronavirus disease 2019 (COVID-19): A narrative review.

Integr Med Res. 2021-12

[6]
Traditional Chinese medicine in COVID-19.

Acta Pharm Sin B. 2021-11

[7]
Traditional Chinese Medicine and Western Medicine Share Similar Philosophical Approaches to Fight COVID-19.

Aging Dis. 2021-8-1

[8]
Drug repurposing screens identify chemical entities for the development of COVID-19 interventions.

Nat Commun. 2021-6-3

[9]
The efficacy and safety of Favipiravir in treatment of COVID-19: a systematic review and meta-analysis of clinical trials.

Sci Rep. 2021-5-26

[10]
The emergence of new strains of SARS-CoV-2. What does it mean for COVID-19 vaccines?

Expert Rev Vaccines. 2021-6

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