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左胸小切口非体外循环冠状动脉旁路移植术的临床研究

The clinical research of off-pump coronary artery bypass grafting by small incision at the left chest.

作者信息

Xiao L-B, Zhang Y-H, Zhou J-W, Yang M, Ling Y-P, Gao Z-S, Wang Y-S

机构信息

Cardio-Thoracic Surgery Department, Cangzhou Center Hospital, Cangzhou, China.

出版信息

Eur Rev Med Pharmacol Sci. 2016;20(2):305-10.

Abstract

OBJECTIVE

To explore the clinical value of off-pump coronary artery bypass grafting by small incision at the left chest, and develop a better surgical regimen for coronary heart disease patients.

PATIENTS AND METHODS

201 coronary heart disease patients who need coronary artery bypass grafting were required and randomly divided into 2 groups including a control group and an observation group. There were 107 cases in the control group who received coronary bypass grafting by extracorporeal circulation; there were 103 cases in the observation group who received off-pump coronary bypass grafting by small incision at the left chest. The duration of the mechanism ventilation, length of stay in ICU, hospitalization time, postoperative drainage volume, and the occurrence rate of complications were recorded and compared.

RESULTS

The duration of mechanism ventilation, length of stay in ICU, hospitalization time and postoperative drainage volume in the control group were (19.21 ± 1.33) hours, (5.08 ± 0.57) days, (21.20 ± 2.34) days and (997.68 ± 96.35) mL, which were (7.73 ± 0.74) hours, (2.83 ± 0.16) days, (15.67 ± 1.18) days and (901.53 ± 89.32) mL in the observation group respectively, with statistical difference between the two groups (p<0.05). The occurrence rates of renal insufficiency and arrhythmia were both 6.54% and 0.97% in the control group and the observation group, respectively. The occurrence rates of postoperative renal insufficiency and arrhythmia in the observation group were both significantly lower than those in the control group, with statistical significance analysis (p < 0.05). Postoperative low cardiac output, second thoracotomy, cerebrovascular disease, pulmonary infection, perioperative cardiac infarction and mortality did not display a significant difference between the two groups (p > 0.05).

CONCLUSIONS

Off-pump coronary artery bypass grafting by small incision at the left chest is a surgical method with less injury and fast recovery, which can be used as the preferred therapeutical method for the coronary heart disease patients who need coronary artery bypass grafting.

摘要

目的

探讨左胸小切口非体外循环冠状动脉搭桥术的临床价值,为冠心病患者制定更佳的手术方案。

患者与方法

选取201例需行冠状动脉搭桥术的冠心病患者,随机分为对照组和观察组。对照组107例,采用体外循环冠状动脉搭桥术;观察组103例,采用左胸小切口非体外循环冠状动脉搭桥术。记录并比较两组患者机械通气时间、ICU住院时间、住院时间、术后引流量及并发症发生率。

结果

对照组机械通气时间、ICU住院时间、住院时间及术后引流量分别为(19.21±1.33)小时、(5.08±0.57)天、(21.20±2.34)天和(997.68±96.35)毫升,观察组分别为(7.73±0.74)小时、(2.83±0.16)天、(15.67±1.18)天和(901.53±89.32)毫升,两组比较差异有统计学意义(p<0.05)。对照组和观察组肾功能不全及心律失常发生率分别为6.54%和0.97%。观察组术后肾功能不全及心律失常发生率均显著低于对照组,差异有统计学意义(p<0.05)。两组术后低心排血量、二次开胸、脑血管疾病、肺部感染、围手术期心肌梗死及死亡率比较差异无统计学意义(p>0.05)。

结论

左胸小切口非体外循环冠状动脉搭桥术是一种创伤小、恢复快的手术方法,可作为需行冠状动脉搭桥术的冠心病患者的首选治疗方法。

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