乙炔铜对环状亚胺离子和氧鎓离子的对映选择性加成反应。
Enantioselective additions of copper acetylides to cyclic iminium and oxocarbenium ions.
作者信息
Liu Jixin, Dasgupta Srimoyee, Watson Mary P
机构信息
Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716, USA.
出版信息
Beilstein J Org Chem. 2015 Dec 22;11:2696-706. doi: 10.3762/bjoc.11.290. eCollection 2015.
Abstract
The development of enantioselective, copper-catalyzed alkynylations of cyclic iminium and oxocarbenium ions is reviewed. The use of chiral copper-based catalysts has enabled high yields and enantioselectivites in the formation of nitrogen- and oxygen-containing heterocycles with α-stereogenic centers. This review highlights both the accomplishments and the future work needed in this important area.
摘要
本文综述了对映选择性、铜催化的环状亚胺离子和氧鎓离子的炔基化反应的发展。手性铜基催化剂的使用使得在形成具有α-立体中心的含氮和含氧杂环化合物时能够实现高产率和对映选择性。本综述突出了这一重要领域已取得的成就以及未来所需开展的工作。
Zotero 插件