Al Salihi S, Jacobi E, Hunter R, Buja M
Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Cardiovasc Pathol. 2016 May-Jun;25(3):203-207. doi: 10.1016/j.carpath.2016.01.001. Epub 2016 Jan 7.
Coronary artery aneurysm is defined as a localized area of dilatation exceeding the diameter of the adjacent normal arterial segment by 50%. Giant aneurysms are those aneurysms that measure greater than 2cm in diameter. There have been many pathologic diseases, including atherosclerosis, that have been implicated in the development of coronary artery aneurysms.
We report a case of a 61-year-old African American male with multiple comorbidities including hypertension, congestive heart failure, abdominal aortic aneurysm, and bilateral iliac aneurysms, who was admitted to our hospital with exacerbation of congestive heart failure. Less than 2weeks after admission, the patient suffered cardiac arrest while receiving dialysis and was unresponsive to resuscitative measures.
Autopsy was performed and revealed significant cardiomyopathy and giant coronary artery aneurysms involving the left anterior descending, left circumflex, and right coronary arteries. Both ventricles showed hypertrophy and dilation with multifocal areas of chronic myocardial scarring.
Coronary artery aneurysms and giant coronary artery aneurysms are an uncommon. As there are few reported cases in the literature, the cause, detection, and treatment of this disease are still largely unknown.
冠状动脉瘤被定义为局部扩张区域,其直径超过相邻正常动脉段直径的50%。巨大动脉瘤是指直径大于2厘米的动脉瘤。包括动脉粥样硬化在内的许多病理疾病都与冠状动脉瘤的发生有关。
我们报告一例61岁非裔美国男性患者,患有多种合并症,包括高血压、充血性心力衰竭、腹主动脉瘤和双侧髂动脉瘤,因充血性心力衰竭加重入住我院。入院后不到2周,患者在接受透析时发生心脏骤停,对复苏措施无反应。
进行尸检,发现严重心肌病和累及左前降支、左旋支和右冠状动脉的巨大冠状动脉瘤。两个心室均显示肥厚和扩张,并伴有多灶性慢性心肌瘢痕形成。
冠状动脉瘤和巨大冠状动脉瘤并不常见。由于文献报道的病例很少,这种疾病的病因、检测和治疗在很大程度上仍然未知。