Jiang Li-Cheng, Cao Jia-Yu, Chen Mao
Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Medicine (Baltimore). 2017 Dec;96(50):e9230. doi: 10.1097/MD.0000000000009230.
Coronary artery aneurysm (CAA) with concomitant aneurysms at multiple sites is quite unusual and rare. The characteristics and the etiology of this phenomenon are unknown.
Herein, we present a case with right coronary aneurysm with concomitant abdominal aorta as well as right renal artery aneurysm. A systematic review of the literatures regarding CAA with other coexisting aneurysms at multiple locations was also conducted on Medline and Embase databases.
A total of 76 patients (male gender: 58; age: 37.4 ± 26.5) including the present case were included in the final study. The most common etiology of CAA with multiple aneurysms was Kawasaki (43.3%) and atherosclerotic disease (16.4%). CAA was the most frequently found at the right coronary artery (62.7%), following, left anterior descending (51%), left main (43.1%), and left circumflex (35.3%). The most common concomitant aneurysms were abdominal aorta (52.6%) and iliac artery (50%). In addition, 60.5% of the patients had an involved bilateral peripheral artery.
CAA with coexisting systemic aneurysms in multiple sites is quite rare. And it usually involves multiple aneurysms at the coronary and bilateral peripheral arteries simultaneously. Currently, there are no general consensus regarding the clinical characteristics, diagnostic method, and treatment of these cases.
冠状动脉瘤(CAA)合并多个部位的动脉瘤非常罕见。这种现象的特征和病因尚不清楚。
在此,我们报告一例右冠状动脉瘤合并腹主动脉及右肾动脉瘤的病例。我们还在Medline和Embase数据库上对有关CAA合并其他多处共存动脉瘤的文献进行了系统综述。
最终研究纳入了包括本病例在内的76例患者(男性58例;年龄37.4±26.5岁)。CAA合并多个动脉瘤的最常见病因是川崎病(43.3%)和动脉粥样硬化疾病(16.4%)。CAA最常发生于右冠状动脉(62.7%),其次是左前降支(51%)、左主干(43.1%)和左旋支(35.3%)。最常见的合并动脉瘤是腹主动脉(52.6%)和髂动脉(50%)。此外,60.5%的患者双侧外周动脉受累。
CAA合并多个部位的系统性动脉瘤非常罕见。它通常同时累及冠状动脉和双侧外周动脉的多个动脉瘤。目前,对于这些病例的临床特征、诊断方法和治疗尚无普遍共识。