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一项针对接受物质使用障碍治疗的成年人的疼痛管理干预的随机试验。

A randomized trial of a pain management intervention for adults receiving substance use disorder treatment.

机构信息

VA Center for Clinical Management Research (CCMR), Veterans Health Administration, Ann Arbor, MI, USA.

Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.

出版信息

Addiction. 2016 Aug;111(8):1385-93. doi: 10.1111/add.13349. Epub 2016 Apr 15.

Abstract

BACKGROUND AND AIMS

Chronic pain is difficult to treat in individuals with substance use disorders and, when not resolved, can have a negative impact on substance use disorder treatment outcomes. This study tested the efficacy of a psychosocial pain management intervention, ImPAT (improving pain during addiction treatment), that combines pain management with content related to managing pain without substance use.

DESIGN

Single-site, parallel-groups randomized controlled trial comparing ImPAT to a supportive psychoeducational control (SPC) condition; follow-up assessments occurred at 3, 6 and 12 months.

SETTING

The Ann Arbor VA Substance Use Disorder treatment program, USA.

PARTICIPANTS

Veterans Health Administration patients {n = 129; mean [standard deviation (SD)], age = 51.7 (9.5); 115 of 129 (89%) male; ImPAT (n = 65); SPC (n = 64)}.

INTERVENTION

ImPAT combines principles of cognitive-behavioral therapy and acceptance-based approaches to pain management with content related to avoiding the use of substances as a coping mechanism for pain. The SPC used a psychoeducational attention control treatment for alcoholism modified to cover other substances in addition to alcohol.

MEASUREMENTS

Primary: Pain intensity over 12 months; secondary: pain-related functioning, frequency of alcohol and drug use over 12 months.

FINDINGS

Primary: randomization to the ImPAT intervention versus SPC predicted significantly lower pain intensity {β [standard error (SE)] = -0.71 (0.29); 95% confidence interval (CI) = -1.29, -0.12}; secondary: relative to the SPC condition, those who received ImPAT also reported improved pain-related functioning [β (SE) = 0.27 (0.11); 95% CI = 0.05, 0.49] and lower frequency of alcohol consumption [β (SE) = -0.77; 95% CI = -1.34, -0.20]. No differences were found between conditions on frequency of drug use over follow-up.

CONCLUSIONS

For adults with pain who are enrolled in addictions treatment, receipt of a psychological pain management intervention (improving pain during addiction treatment) reduced pain and alcohol use and improves pain-related functioning over 12 months relative to a matched-attention control condition.

摘要

背景和目的

慢性疼痛在物质使用障碍患者中难以治疗,且如果未得到解决,可能会对物质使用障碍的治疗结果产生负面影响。本研究测试了一种心理社会疼痛管理干预措施 ImPAT(改善成瘾治疗期间的疼痛)的疗效,该措施将疼痛管理与与避免使用物质作为应对疼痛的手段相关的内容相结合。

设计

单站点、平行组随机对照试验,将 ImPAT 与支持性心理教育对照(SPC)条件进行比较;在 3、6 和 12 个月时进行随访评估。

地点

美国安阿伯退伍军人事务部物质使用障碍治疗项目。

参与者

退伍军人健康管理局患者(n=129;平均[标准差(SD)],年龄 51.7[9.5];129 人中 115 名[89%]为男性;ImPAT[n=65];SPC[n=64])。

干预措施

ImPAT 将认知行为疗法和接受为基础的疼痛管理原则与与避免将物质用作疼痛应对机制相关的内容相结合。SPC 使用了一种酒精中毒的心理教育注意力控制治疗方法,经过修改,除了酒精之外,还涵盖了其他物质。

测量

主要指标:12 个月内的疼痛强度;次要指标:12 个月内的疼痛相关功能、酒精和药物使用频率。

发现

主要指标:与 SPC 相比,随机分配到 ImPAT 干预组的患者疼痛强度显著降低(β[标准误差(SE)]=-0.71[0.29];95%置信区间(CI)=-1.29,-0.12);次要指标:与 SPC 条件相比,接受 ImPAT 的患者报告疼痛相关功能得到改善(β[SE]=0.27[0.11];95%CI=0.05,0.49),且酒精消费频率降低(β[SE]=-0.77;95%CI=-1.34,-0.20)。在随访期间,两种条件之间在药物使用频率上没有差异。

结论

对于参加成瘾治疗的患有疼痛的成年人来说,与匹配的注意力控制条件相比,接受心理疼痛管理干预(改善成瘾治疗期间的疼痛)可在 12 个月内减轻疼痛和减少酒精使用,改善疼痛相关功能。

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