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牛链球菌属引起的儿童脑膜炎的诊断与治疗

Diagnosis and Treatment of Childhood Meningitis Caused by Streptococcus bovis Group.

作者信息

Hede Sannya Vidyadhar

机构信息

Boston Children's Hospital, 300 Longwood Ave., Boston, MA, 02115, USA.

出版信息

Curr Infect Dis Rep. 2016 Mar;18(4):11. doi: 10.1007/s11908-016-0519-8.

Abstract

Streptococcus bovis is a rare, but important cause of bacterial meningitis in children. Since its discovery in the early 1970s, the pathogen has undergone multiple taxonomic changes producing four distinct subspecies today, the most prevalent of which is S. gallolyticus subsp pasteurianus in infants and children. While initially reported as sporadic case reports, there is a growing body of literature documenting invasive disease primarily in neonates and infants clinically indistinguishable from group B streptococcus. In this review, I discuss the taxonomic evolution of S. bovis meningitis and its subsequent clinical diagnosis, manifestations and treatment in children.

摘要

牛链球菌是儿童细菌性脑膜炎的一种罕见但重要的病因。自20世纪70年代初被发现以来,该病原体经历了多次分类学变化,如今产生了四个不同的亚种,其中最常见的是婴儿和儿童中的解没食子酸链球菌巴氏亚种。虽然最初报告为散发病例报告,但越来越多的文献记录了主要发生在新生儿和婴儿中的侵袭性疾病,临床上与B组链球菌难以区分。在这篇综述中,我讨论了牛链球菌脑膜炎的分类学演变及其在儿童中的后续临床诊断、表现和治疗。

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