一名婴儿患解没食子酸链球菌亚种巴斯德亚种脑膜炎。
Streptococcus gallolyticus subsp. pasteurianus meningitis in an infant.
作者信息
Takahashi Yoshiko, Ishiwada Naruhiko, Tanaka Junko, Okusu Kiyofumi, Ichimura Sadahiro, Hishiki Haruka, Ota Setsuo, Kohno Yoichi
机构信息
Department of Pediatrics, Teikyo University Chiba Medical Center, Chiba, Japan; Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, Japan.
出版信息
Pediatr Int. 2014 Apr;56(2):282-5. doi: 10.1111/ped.12254.
Streptococcus gallolyticus subsp. pasteurianus was formerly classified as S. bovis biotype II/2, which is recognized as a rare cause of neonatal sepsis and meningitis. Since the taxonomy classification change, there have not been many reports of meningitis due to S. gallolyticus subsp. pasteurianus. Moreover, the pathogenesis of late onset S. gallolyticus subsp. pasteurianus meningitis in infants is unclear. Here we report a case of meningitis in a 5-week-old infant with preceding diarrhea. S. bovis biotype II/2 was isolated from the blood, cerebrospinal fluid and stool, and then was identified as S. gallolyticus subsp. pasteurianus on 16S rRNA gene sequencing. Isolates from all three sample types had identical profiles on pulsed-field gel electrophoresis. The intestinal tract was thought to be the source of the infection.
解没食子酸链球菌巴斯德亚种以前被归类为牛链球菌生物型II/2，它被认为是新生儿败血症和脑膜炎的罕见病因。自分类学分类改变以来，关于解没食子酸链球菌巴斯德亚种引起脑膜炎的报道并不多。此外，婴儿迟发性解没食子酸链球菌巴斯德亚种脑膜炎的发病机制尚不清楚。在此，我们报告一例5周大婴儿在腹泻前驱症状后发生脑膜炎的病例。从血液、脑脊液和粪便中分离出牛链球菌生物型II/2，然后通过16S rRNA基因测序鉴定为解没食子酸链球菌巴斯德亚种。来自所有三种样本类型的分离株在脉冲场凝胶电泳上具有相同的图谱。肠道被认为是感染源。
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