Hosier Gregory W, Phillips Stephen J, Doucette Steve P, Magee Kirk D, Gubitz Gordon J
*Faculty of Medicine,Queen Elizabeth II Health Sciences Centre,Dalhousie University,Halifax,NS.
†Division of Neurology,Queen Elizabeth II Health Sciences Centre,Dalhousie University,Halifax,NS.
CJEM. 2016 Sep;18(5):331-9. doi: 10.1017/cem.2016.3. Epub 2016 Feb 16.
Retrospective chart review of all patients discharged from EDs in our district from January 1, 2011 to December 31, 2012 with a diagnosis of TIA. Cox proportional hazards models, Kaplan-Meier survival curve, and propensity matched analyses were used to evaluate 90-day mortality and readmission.
Of the 686 patients seen in the ED for TIA, 88.3% received computed tomography (CT) scanning, 86.3% received an electrocardiogram (ECG), 35% received vascular imaging within 24 hours of triage, 36% were seen in a neurovascular clinic, and 4.2% experienced stroke, myocardial infarction, or vascular death within 90 days. Rates of antithrombotic use were increased in patients seen in a neurovascular clinic compared to those who were not (94% v. 86.3%, p<0.0001). After adjustment for age, sex, vascular disease risk factors, and stroke symptoms, the risk of readmission for stroke, myocardial infarction, or vascular death was lower for those seen in a neurovascular clinic compared to those who were not (adjusted hazard ratio 0.28; 95% confidence interval 0.08-0.99, p=0.048).
The majority of patients in our study were treated with antithrombotic agents in the ED and investigated with CT and ECG within 24 hours; however, vascular imaging and neurovascular clinic follow-up were underutilized. For those with neurovascular clinic follow-up, there was an association with reduced risk of subsequent stroke, myocardial infarction, or vascular death.
1)评估新斯科舍省首都地区卫生局急诊科对短暂性脑缺血发作(TIA)的管理是否遵循加拿大最佳实践建议;2)评估在专门的门诊神经血管诊所接受随访的影响。
对2011年1月1日至2012年12月31日期间在本地区急诊科出院且诊断为TIA的所有患者进行回顾性病历审查。使用Cox比例风险模型、Kaplan-Meier生存曲线和倾向匹配分析来评估90天死亡率和再入院情况。
在急诊科因TIA就诊的686例患者中,88.3%接受了计算机断层扫描(CT),86.3%接受了心电图(ECG)检查,35%在分诊后24小时内接受了血管成像检查,36%在神经血管诊所就诊,4.2%在90天内发生了中风、心肌梗死或血管性死亡。与未在神经血管诊所就诊的患者相比,在神经血管诊所就诊的患者抗血栓药物使用率更高(94%对86.3%,p<0.0001)。在调整年龄、性别、血管疾病危险因素和中风症状后,与未在神经血管诊所就诊的患者相比,在神经血管诊所就诊的患者中风、心肌梗死或血管性死亡再入院风险更低(调整后的风险比为0.28;95%置信区间为0.08-0.99,p=0.048)。
我们研究中的大多数患者在急诊科接受了抗血栓药物治疗,并在24小时内接受了CT和ECG检查;然而,血管成像和神经血管诊所随访的利用率较低。对于那些接受神经血管诊所随访的患者,其随后发生中风、心肌梗死或血管性死亡的风险降低。