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短暂性脑缺血发作:急诊科的管理及门诊神经血管诊所的影响

Transient ischemic attack: management in the emergency department and impact of an outpatient neurovascular clinic.

作者信息

Hosier Gregory W, Phillips Stephen J, Doucette Steve P, Magee Kirk D, Gubitz Gordon J

机构信息

*Faculty of Medicine,Queen Elizabeth II Health Sciences Centre,Dalhousie University,Halifax,NS.

†Division of Neurology,Queen Elizabeth II Health Sciences Centre,Dalhousie University,Halifax,NS.

出版信息

CJEM. 2016 Sep;18(5):331-9. doi: 10.1017/cem.2016.3. Epub 2016 Feb 16.

DOI:10.1017/cem.2016.3
PMID:26879765
Abstract

OBJECTIVES

  1. To evaluate whether transient ischemic attack (TIA) management in emergency departments (EDs) of the Nova Scotia Capital District Health Authority followed Canadian Best Practice Recommendations, and 2) to assess the impact of being followed up in a dedicated outpatient neurovascular clinic.

METHODS

Retrospective chart review of all patients discharged from EDs in our district from January 1, 2011 to December 31, 2012 with a diagnosis of TIA. Cox proportional hazards models, Kaplan-Meier survival curve, and propensity matched analyses were used to evaluate 90-day mortality and readmission.

RESULTS

Of the 686 patients seen in the ED for TIA, 88.3% received computed tomography (CT) scanning, 86.3% received an electrocardiogram (ECG), 35% received vascular imaging within 24 hours of triage, 36% were seen in a neurovascular clinic, and 4.2% experienced stroke, myocardial infarction, or vascular death within 90 days. Rates of antithrombotic use were increased in patients seen in a neurovascular clinic compared to those who were not (94% v. 86.3%, p<0.0001). After adjustment for age, sex, vascular disease risk factors, and stroke symptoms, the risk of readmission for stroke, myocardial infarction, or vascular death was lower for those seen in a neurovascular clinic compared to those who were not (adjusted hazard ratio 0.28; 95% confidence interval 0.08-0.99, p=0.048).

CONCLUSION

The majority of patients in our study were treated with antithrombotic agents in the ED and investigated with CT and ECG within 24 hours; however, vascular imaging and neurovascular clinic follow-up were underutilized. For those with neurovascular clinic follow-up, there was an association with reduced risk of subsequent stroke, myocardial infarction, or vascular death.

摘要

目的

1)评估新斯科舍省首都地区卫生局急诊科对短暂性脑缺血发作(TIA)的管理是否遵循加拿大最佳实践建议;2)评估在专门的门诊神经血管诊所接受随访的影响。

方法

对2011年1月1日至2012年12月31日期间在本地区急诊科出院且诊断为TIA的所有患者进行回顾性病历审查。使用Cox比例风险模型、Kaplan-Meier生存曲线和倾向匹配分析来评估90天死亡率和再入院情况。

结果

在急诊科因TIA就诊的686例患者中,88.3%接受了计算机断层扫描(CT),86.3%接受了心电图(ECG)检查,35%在分诊后24小时内接受了血管成像检查,36%在神经血管诊所就诊,4.2%在90天内发生了中风、心肌梗死或血管性死亡。与未在神经血管诊所就诊的患者相比,在神经血管诊所就诊的患者抗血栓药物使用率更高(94%对86.3%,p<0.0001)。在调整年龄、性别、血管疾病危险因素和中风症状后,与未在神经血管诊所就诊的患者相比,在神经血管诊所就诊的患者中风、心肌梗死或血管性死亡再入院风险更低(调整后的风险比为0.28;95%置信区间为0.08-0.99,p=0.048)。

结论

我们研究中的大多数患者在急诊科接受了抗血栓药物治疗,并在24小时内接受了CT和ECG检查;然而,血管成像和神经血管诊所随访的利用率较低。对于那些接受神经血管诊所随访的患者,其随后发生中风、心肌梗死或血管性死亡的风险降低。

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