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短暂性脑缺血发作治疗的最新进展

Recent advances in the management of transient ischemic attacks.

作者信息

Ortiz-Garcia Jorge, Gomez Camilo R, Schneck Michael J, Biller José

机构信息

Department of Neurology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

Department of Neurology, University of Missouri Columbia, Columbia, MO, USA.

出版信息

Fac Rev. 2022 Jul 22;11:19. doi: 10.12703/r/11-19. eCollection 2022.

Abstract

Transient ischemic attack (TIA) constitutes an important clinical condition, indicating the presence of considerable risk for a subsequent ischemic stroke. Its prompt diagnosis and management have the potential for reducing the risk of neurologic disability, highlighting the critical need to prioritize the care of patients with TIA. The risk of ischemic stroke following a TIA is directly related to its etiopathogenesis, and recognizable causes are commonly categorized within one of three domains: cerebrovascular pathology, cardiac dysfunction, and hematologic disorders. Therefore, the clinical approach to patients suspected of having suffered a TIA demands a comprehensive evaluation, including testing of possible etiologic conditions in all three of these domains, best carried out in an expedited fashion since the stroke risk is greatest in the hours and days that follow the index event. The present is a review of the existing literature addressing the diagnosis, evaluation, prioritization, and management strategies available to clinicians who provide care to patients with TIA.

摘要

短暂性脑缺血发作(TIA)是一种重要的临床病症,表明随后发生缺血性中风的风险相当大。其及时诊断和治疗有可能降低神经功能残疾的风险,突出了优先照顾TIA患者的迫切需要。TIA后发生缺血性中风的风险与其病因直接相关,可识别的病因通常分为三个领域之一:脑血管病变、心脏功能障碍和血液系统疾病。因此,对疑似患有TIA的患者的临床处理需要进行全面评估,包括对所有这三个领域中可能的病因情况进行检测,最好尽快进行,因为在索引事件后的数小时和数天内中风风险最大。本文是对现有文献的综述,涉及为TIA患者提供护理的临床医生可用的诊断、评估、优先排序和管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce03/9340656/b7cbf6c25bcf/facrev-11-19-g001.jpg

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