Zhou Shukui, Zhang Kaile, Atala Anthony, Khoury Oula, Murphy Sean V, Zhao Weixin, Fu Qiang
Department of Urology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Wake Forest Institute for Regenerative Medicine, Winston Salem, NC, USA.
Stem Cells Int. 2016;2016:7060975. doi: 10.1155/2016/7060975. Epub 2016 Jan 10.
Stress urinary incontinence (SUI) is a common urinary system disease that mostly affects women. Current treatments still do not solve the critical problem of urethral sphincter dysfunction. In recent years, there have been major developments in techniques to obtain, culture, and characterize autologous stem cells as well as many studies describing their applications for the treatment of SUI. In this paper, we review recent publications and clinical trials investigating the applications of several stem cell types as potential treatments for SUI and the underlying challenges of such therapy.
压力性尿失禁（SUI）是一种常见的泌尿系统疾病，主要影响女性。目前的治疗方法仍未解决尿道括约肌功能障碍这一关键问题。近年来，在获取、培养和鉴定自体干细胞的技术方面取得了重大进展，同时也有许多研究描述了它们在治疗SUI中的应用。在本文中，我们综述了最近的出版物和临床试验，这些研究调查了几种干细胞类型作为SUI潜在治疗方法的应用以及这种治疗的潜在挑战。
