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转移性脊索瘤:细针穿刺活检的诊断挑战

Metastatic Chordoma: A Diagnostic Challenge on Fine Needle Aspiration.

作者信息

Tranesh Ghassan, Nassar Aziza

机构信息

Department of Pathology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.

出版信息

Case Rep Pathol. 2016;2016:2187290. doi: 10.1155/2016/2187290. Epub 2016 Jan 3.

Abstract

Chordomas are primary low grade malignant tumors of bone that usually arise within both ends of axial skeleton. The Notochord is a midline, ectoderm-derived structure that defines the phylum of chordates. Chordomas may pose difficult diagnostic challenges when encountered in secondary locations, such as lungs or other parenchymatous organs. We report the cytologic findings of a metastatic chordoma sampled through CT-scan guided fine needle aspiration (FNA) of lower lobe lung nodule in a 54-year-old man diagnosed with recurrent chordoma involving the lumber spine and paraspinal region.

摘要

脊索瘤是原发性低度恶性骨肿瘤,通常发生于中轴骨骼的两端。脊索是一种中线的、外胚层来源的结构,它定义了脊索动物门。当在肺部或其他实质器官等继发性部位遇到脊索瘤时,可能会带来诊断难题。我们报告了一名54岁男性的转移性脊索瘤的细胞学检查结果,该患者通过CT引导下经皮肺穿刺细针抽吸活检(FNA)对下叶肺结节进行采样,患者被诊断为复发性脊索瘤,累及腰椎和椎旁区域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2db9/4735921/a3d6f3b9f592/CRIPA2016-2187290.001.jpg

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