Grandahl Mia Gall, Nielsen Svend Erik, Koerner Ejnar Alex, Schultz Helga Holm, Arnfred Sidse Marie
a Psychiatric Center Nordsjaelland , Hilleroed, Denmark ;
b Department of Oncology and Palliation, North Zealand Hospital , Hilleroed, Denmar ;
Nord J Psychiatry. 2016 Aug;70(6):413-7. doi: 10.3109/08039488.2016.1141982. Epub 2016 Feb 16.
Background Delirium is a frequent psychiatric complication to cancer, but rarely recognized by oncologists. Aims 1. To estimate the prevalence of delirium among inpatients admitted at an oncological cancer ward 2. To investigate whether simple clinical factors predict delirium 3. To examine the value of cognitive testing in the assessment of delirium. Methods On five different days, we interviewed and assessed patients admitted to a Danish cancer ward. The World Health Organization International Classification of Diseases Version 10, WHO ICD-10 Diagnostic System and the Confusion Assessment Method (CAM) were used for diagnostic categorization. Clinical information was gathered from medical records and all patients were tested with Mini Cognitive Test, The Clock Drawing Test, and the Digit Span Test. Results 81 cancer patients were assessed and 33% were diagnosed with delirium. All delirious participants were CAM positive. Poor performance on the cognitive tests was associated with delirium. Medical records describing CNS metastases, benzodiazepine or morphine treatment were associated with delirium. Conclusions Delirium is prevalent among cancer inpatients. The Mini Cognitive Test, The Clock Drawing Test, and the Digit Span Test can be used as screening tools for delirium among inpatients with cancer, but even in synergy, they lack specificity. Combining cognitive testing and attention to nurses' records might improve detection, yet further studies are needed to create a more detailed patient profile for the detection of delirium.
谵妄是癌症常见的精神并发症,但肿瘤学家很少认识到这一点。
在五个不同的日子里,我们对丹麦一家癌症病房收治的患者进行了访谈和评估。使用世界卫生组织国际疾病分类第10版(WHO ICD - 10)诊断系统和谵妄评定方法(CAM)进行诊断分类。从病历中收集临床信息,所有患者均接受简易认知测试、画钟试验和数字广度测试。
对81名癌症患者进行了评估,33%被诊断为谵妄。所有谵妄患者CAM评定均为阳性。认知测试表现不佳与谵妄有关。记录有中枢神经系统转移、苯二氮䓬类药物或吗啡治疗的病历与谵妄有关。
谵妄在癌症住院患者中很常见。简易认知测试、画钟试验和数字广度测试可作为癌症住院患者谵妄的筛查工具,但即使联合使用,它们也缺乏特异性。将认知测试与关注护士记录相结合可能会提高检测率,但仍需要进一步研究以建立更详细的患者资料用于谵妄的检测。