Emerenziani Gian Pietro, Gallotta Maria Chiara, Migliaccio Silvia, Greco Emanuela A, Marocco Chiara, di Lazzaro Luca, Fornari Rachele, Lenzi Andrea, Baldari Carlo, Guidetti Laura
Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Piazza Lauro de Bosis 6, 00135 Rome, Italy; Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Piazza Lauro de Bosis 6, 00135 Rome, Italy.
Int J Endocrinol. 2016;2016:6739150. doi: 10.1155/2016/6739150. Epub 2016 Jan 14.
Aim of the study was to examine cardiorespiratory parameters at individual ventilatory threshold (IVT) and peak exercise capacity ([Formula: see text]) in outpatient diabetic and sarcopenic obese subjects. Seventeen obese subjects (BMI: 36.6 ± 4.1 kg·m(-1)) and sixteen SO subjects (BMI: 37.0 ± 7.3 kg·m(-1)) were compared with sixteen T2DM subjects (BMI: 37.7 ± 5.6 kg·m(-1)). All groups performed an incremental exercise test on a treadmill according to their physical ability. [Formula: see text], %HRmax, and maximal metabolic equivalent (METmax) were evaluated at maximal effort. Moreover, [Formula: see text], %[Formula: see text], %HRmax, %HRR, ΔHR, and METivt were assessed at IVT. No significant differences were found in any physiological parameters at maximal effort ([Formula: see text], %HRmax, and METmax) in all groups. On the contrary, [Formula: see text], %[Formula: see text], %HRmax, %HRR, ΔHR, and METivt were significantly lower in T2DM subjects as compared to OB and SO subjects at IVT (p < 0.05). Our results show that while at maximal effort there are no differences among groups, at IVT the physiological parameters are lower in T2DM subjects than in OB and SO subjects. Therefore, due to the differences observed in the groups, we suggest usng the IVT as a useful parameter to prescribe aerobic exercise in obese with sarcopenia or diabetes mellitus conditions.
本研究的目的是在门诊糖尿病和肌肉减少性肥胖受试者中,检测个体通气阈值(IVT)和运动能力峰值([公式:见原文])时的心肺参数。将17名肥胖受试者(BMI:36.6±4.1kg·m⁻¹)和16名肌肉减少性肥胖受试者(BMI:37.0±7.3kg·m⁻¹)与16名2型糖尿病受试者(BMI:37.7±5.6kg·m⁻¹)进行比较。所有组根据其身体能力在跑步机上进行递增运动试验。在最大努力时评估[公式:见原文]、%HRmax和最大代谢当量(METmax)。此外,在IVT时评估[公式:见原文]、%[公式:见原文]、%HRmax、%HRR、ΔHR和METivt。所有组在最大努力时([公式:见原文]、%HRmax和METmax)的任何生理参数均未发现显著差异。相反,在IVT时,2型糖尿病受试者的[公式:见原文]、%[公式:见原文]、%HRmax、%HRR、ΔHR和METivt显著低于肥胖和肌肉减少性肥胖受试者(p<0.05)。我们的结果表明,虽然在最大努力时各组之间没有差异,但在IVT时,2型糖尿病受试者的生理参数低于肥胖和肌肉减少性肥胖受试者。因此,由于各组之间观察到的差异,我们建议将IVT作为为患有肌肉减少症或糖尿病的肥胖者开具有氧运动处方的有用参数。