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择期结肠手术的抗菌肠道准备

Antimicrobial Bowel Preparation for Elective Colon Surgery.

作者信息

Fry Donald E

机构信息

1 Department of Surgery, Northwestern University Feinberg School of Medicine , Chicago, Illinois.

2 Department of Surgery, University of New Mexico School of Medicine , Albuquerque, New Mexico .

出版信息

Surg Infect (Larchmt). 2016 Jun;17(3):269-74. doi: 10.1089/sur.2015.271. Epub 2016 Feb 17.

Abstract

BACKGROUND

Mechanical bowel preparation continues to be a controversial subject for the pre-operative management of patients undergoing elective colon resection.

METHODS

The English literature on bowel preparation was searched to identify pertinent publications.

RESULTS

The published literature over the past 80 y confirms that mechanical bowel preparation alone does not reduce surgical site infections. However, the use of appropriate oral antibiotics following mechanical bowel preparation with pre-operative systemic antibiotics reduces rates of surgical site infections and anastomotic leaks when compared with systemic antibiotics alone.

CONCLUSIONS

Mechanical bowel preparation with pre-operative oral antibiotics and pre-operative systemic antibiotics are the standard of care for elective colon surgery. Refinement in methods of bowel preparation needs additional clinical investigations to further enhance outcomes.

摘要

背景

对于接受择期结肠切除术患者的术前管理,机械性肠道准备仍然是一个有争议的话题。

方法

检索关于肠道准备的英文文献以确定相关出版物。

结果

过去80年发表的文献证实,单纯机械性肠道准备并不能降低手术部位感染率。然而,与单独使用全身抗生素相比,在机械性肠道准备后使用适当的口服抗生素并联合术前全身抗生素可降低手术部位感染率和吻合口漏发生率。

结论

术前口服抗生素联合术前全身抗生素进行机械性肠道准备是择期结肠手术的标准治疗方法。肠道准备方法的改进需要更多的临床研究以进一步改善治疗效果。

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