果蝇轴突发育能让我们了解到哪些关于神经再生的知识？ - Suppr

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What can Drosophila axonal development teach us about nerve regeneration?

作者信息

Araújo Sofia J

机构信息

Institut de Biologia Molecular de Barcelona (IBMB-CSIC), Parc Cientific de Barcelona, Barcelona, Spain.

出版信息

Neural Regen Res. 2015 Dec;10(12):1917-8. doi: 10.4103/1673-5374.169626.

DOI:10.4103/1673-5374.169626

PMID:26889166

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4730802/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f63/4730802/c3c2d0613763/NRR-10-1917-g001.jpg

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c-Jun N-terminal kinase 1 (JNK1) is required for coordination of netrin signaling in axon guidance.c-Jun氨基末端激酶1（JNK1）是轴突导向中netrin信号协调所必需的。

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Axon regrowth during development and regeneration following injury share molecular mechanisms.在发育过程中和损伤后的再生中，轴突的再生共享分子机制。

Curr Biol. 2012 Oct 9;22(19):1774-82. doi: 10.1016/j.cub.2012.07.044. Epub 2012 Aug 23.

Axon degeneration and regeneration: insights from Drosophila models of nerve injury.轴突变性和再生：来自果蝇神经损伤模型的见解。

Annu Rev Cell Dev Biol. 2012;28:575-97. doi: 10.1146/annurev-cellbio-101011-155836. Epub 2012 Jul 23.

Microfluidic chips for in vivo imaging of cellular responses to neural injury in Drosophila larvae.用于在体成像果蝇幼虫神经损伤细胞反应的微流控芯片。

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