Pham My, Awad Mohammed
Department of Neurosurgery, Royal Melbourne Hospital, Melbourne, Victoria 3050, Australia.
Asian J Neurosurg. 2016 Jan-Mar;11(1):73. doi: 10.4103/1793-5482.165783.
Neurolymphomatosis (NL) is a rare neurological manifestation of lymphoma characterized by malignant lymphoma cells infiltrating cranial or peripheral nerve, or their roots. We present the first reported Australian case of a patient whose initial presentation of relapsed mantle cell lymphoma was NL. Our case highlights that clinical and imaging findings of NL often mimic other neuropathies, and hence presents unique challenges that may lead to delayed diagnosis and management. We emphasize the importance of considering NL in the differential diagnosis and combining imaging with other diagnostic modalities such as lumbar puncture (LP) to aid in the diagnosis of NL particularly where there is acute neurological deterioration.
神经淋巴瘤（NL）是淋巴瘤一种罕见的神经表现形式，其特征为恶性淋巴瘤细胞浸润颅神经或周围神经及其神经根。我们报告了澳大利亚首例初发表现为复发套细胞淋巴瘤且以神经淋巴瘤为表现的病例。我们的病例强调，神经淋巴瘤的临床和影像学表现常与其他神经病变相似，因此带来了独特的挑战，可能导致诊断和治疗延迟。我们强调在鉴别诊断中考虑神经淋巴瘤的重要性，并将影像学与其他诊断方法（如腰椎穿刺）相结合，以辅助神经淋巴瘤的诊断，尤其是在出现急性神经功能恶化的情况下。
