Kahraman Turhan, Savci Sema, Coskuner Poyraz Esra, Ozakbas Serkan, Idiman Egemen
Dokuz Eylül University, School of Physical Therapy and Rehabilitation, Izmir, Turkey.
Dokuz Eylül University, Faculty of Medicine, Department of Neurology, Izmir, Turkey.
NeuroRehabilitation. 2016;38(1):7-14. doi: 10.3233/NRE-151290.
The Expanded Disability Status Scale (EDSS) is a well-established clinical measure to assess disability in multiple sclerosis (MS). Gait dysfunction is primarily considered for scoring only above EDSS 3.5. However, the changes in functional systems in below EDSS 3.5 may result gait disturbances.
To determine the distinctive ability of the EDSS 2.0 in terms of walking impairment as well as fatigue, depression, and quality of life in persons with MS with mild disability.
All participants underwent the neurological examination for generating an EDSS score and completed the measures of walking performance, as well as other measures of fatigue, depression, and quality of life. The participants were divided into two groups according to the EDSS scores (i.e. EDSS <2.0 and 2.0-3.5).
Participants with EDSS 2.0-3.5 had significantly worse walking performance, as well as fatigue, depression, and quality of life levels than the participants with EDSS <2.0 (p < 0.05). The EDSS significantly correlated with the measures of walking performance, as well as other measures of fatigue, depression, and quality of life.
The EDSS 2.0 has a distinctive ability in terms of walking impairment as well as fatigue, depression, and quality of life.
扩展残疾状态量表（EDSS）是一种成熟的用于评估多发性硬化症（MS）患者残疾程度的临床指标。步态功能障碍主要仅在EDSS评分高于3.5时才纳入评分考量。然而，EDSS评分低于3.5时功能系统的变化可能导致步态障碍。
确定EDSS 2.0在评估轻度残疾的MS患者步行功能障碍以及疲劳、抑郁和生活质量方面的独特能力。
所有参与者均接受神经系统检查以得出EDSS评分，并完成步行能力测量以及其他疲劳、抑郁和生活质量测量。参与者根据EDSS评分分为两组（即EDSS <2.0和2.0 - 3.5）。
与EDSS <2.0的参与者相比，EDSS 2.0 - 3.5的参与者在步行能力、疲劳、抑郁和生活质量水平方面明显更差（p < 0.05）。EDSS与步行能力测量以及其他疲劳、抑郁和生活质量测量显著相关。
EDSS 2.0在步行功能障碍以及疲劳、抑郁和生活质量方面具有独特能力。
