Verim Ayşegül, Şeneldir Lütfü, Naiboğlu Barış, Tepe Karaca Çiğdem, Kadıoğlu Dinçer, Zer Toros Sema
Department of Otolaryngology, Haydarpaşa Numune Training and Research Hospital, 34668 Üsküdar, İstanbul, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2016;26(2):65-72. doi: 10.5606/kbbihtisas.2016.78972.
This study aims to investigate the influence of laryngopharyngeal reflux on the improvement of chronic rhinosinusitis (CRS) in patients who underwent endoscopic sinus surgery (ESS).
A total of 48 patients (28 males, 20 females; mean age 41.6±15.1 years; range 18 to 75 years) with CRS without polyposis were assessed for the presence of gastric reflux with Reflux Symptom Index (RSI) and Reflux Finding Scores (RFS) before undergoing primary ESS. Patients with a RSI >12 and RFS >7 were included in the reflux(+) and those with either score under these cutoffs in the reflux(-) group. Improvement scores were accepted as the difference between preoperative scores and postoperative sixth-month Lund-Mackay Radiology Scores, Lund-Kennedy Endoscopy Scores (LKES), and Sinusitis Symptom Scores (SSS).
There was no significant difference between improvements of the reflux(+) and reflux(-) groups in terms of radiology, endoscopy, and symptom scores (p>0.05). However, preoperative and postoperative six-month radiology scores were significantly higher in reflux(+) patients (p<0.01). Also, postoperative six-month LKES were significantly higher in reflux(+) patients. No statistically significant differences were detected between preoperative and postoperative six-month SSS in reflux(+) or reflux(-) patients.
Laryngopharyngeal reflux was associated with worse radiology and endoscopy scores in CRS without polyposis; however, it had no role on the improvement scores after primary ESS.
本研究旨在调查喉咽反流对接受鼻内镜鼻窦手术(ESS)的慢性鼻窦炎(CRS)患者病情改善的影响。
共有48例无息肉的慢性鼻窦炎患者(男性28例,女性20例;平均年龄41.6±15.1岁;年龄范围18至75岁)在接受初次ESS之前,通过反流症状指数(RSI)和反流发现评分(RFS)评估胃反流情况。RSI>12且RFS>7的患者被纳入反流(+)组,而RSI和RFS低于这些临界值的患者被纳入反流(-)组。改善评分定义为术前评分与术后第六个月的Lund-Mackay放射学评分、Lund-Kennedy内镜评分(LKES)和鼻窦炎症状评分(SSS)之间的差值。
反流(+)组和反流(-)组在放射学、内镜检查和症状评分方面的改善情况无显著差异(p>0.05)。然而,反流(+)组患者术前和术后六个月的放射学评分显著更高(p<0.01)。此外,反流(+)组患者术后六个月的LKES也显著更高。反流(+)组或反流(-)组患者术前和术后六个月的SSS之间未检测到统计学上的显著差异。
喉咽反流与无息肉的慢性鼻窦炎患者较差的放射学和内镜检查评分相关;然而,它对初次ESS后的改善评分没有影响。