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用于磁共振成像的铁羧麦芽糖给药的安全性与技术

Safety and technique of ferumoxytol administration for MRI.

作者信息

Vasanawala Shreyas S, Nguyen Kim-Lien, Hope Michael D, Bridges Mellena D, Hope Thomas A, Reeder Scott B, Bashir Mustafa R

机构信息

Department of Radiology, Stanford University, Stanford, CA.

Department of Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles.

出版信息

Magn Reson Med. 2016 May;75(5):2107-11. doi: 10.1002/mrm.26151. Epub 2016 Feb 18.

DOI:10.1002/mrm.26151
PMID:26890830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4854636/
Abstract

Ferumoxytol is an ultrasmall superparamagnetic iron oxide agent marketed for the treatment of anemia. There has been increasing interest in its properties as an MRI contrast agent as well as greater awareness of its adverse event profile. This mini-review summarizes the current state of knowledge of the risks of ferumoxytol and methods of administration.

摘要

菲洛赛托是一种用于治疗贫血的超小型超顺磁性氧化铁制剂。人们对其作为磁共振成像(MRI)造影剂的特性越来越感兴趣,同时对其不良事件谱也有了更多认识。这篇小型综述总结了目前关于菲洛赛托风险及给药方法的知识现状。

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本文引用的文献

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Curr Probl Diagn Radiol. 2016 May-Jun;45(3):174-9. doi: 10.1067/j.cpradiol.2015.08.003. Epub 2015 Aug 11.
2
A Phase I Dosing Study of Ferumoxytol for MR Lymphography at 3 T in Patients With Prostate Cancer.钆贝葡胺用于前列腺癌患者3T磁共振淋巴造影的I期剂量研究。
AJR Am J Roentgenol. 2015 Jul;205(1):64-9. doi: 10.2214/AJR.14.13009.
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Nephrogenic Systemic Fibrosis Manifesting a Decade After Exposure to Gadolinium.钆暴露 10 年后发生的肾源性系统性纤维化。
JAMA Dermatol. 2015 Oct;151(10):1117-20. doi: 10.1001/jamadermatol.2015.0976.
4
Ferumoxytol as an intraprostatic MR contrast agent for lymph node mapping of the prostate: a feasibility study in non-human primates.非那雄胺作为一种用于前列腺淋巴结造影的前列腺内磁共振造影剂:在非人类灵长类动物中的可行性研究。
Acta Radiol. 2016 Nov;57(11):1396-1401. doi: 10.1177/0284185115586023. Epub 2016 Jul 21.
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Mathematical optimization of contrast concentration for T1-weighted spoiled gradient echo imaging.T1加权扰相梯度回波成像中对比剂浓度的数学优化
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Intracranial Gadolinium Deposition after Contrast-enhanced MR Imaging.颅内钆沉积与对比增强磁共振成像后。
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