睡眠障碍与损伤之间的关联：一项基于全国人口的回顾性队列研究。

Association between sleep disorders and injury: a nationwide population-based retrospective cohort study.

作者信息

Lin Chia-Ling, Chung Chi-Hsiang, Tsai Yu-Hsia, Chien Wu-Chien

机构信息

School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan Department of Nursing, Chang Gung University of Science and Technology, Taoyuan, Taiwan.

Taiwanese Injury Prevention and Safety Promotion Association, Taipei, Taiwan.

出版信息

Inj Prev. 2016 Oct;22(5):342-6. doi: 10.1136/injuryprev-2015-041844. Epub 2016 Feb 18.

DOI:10.1136/injuryprev-2015-041844

PMID:26892317

Abstract

BACKGROUND

The evidence is insufficient for the association between the exposure of sleep disorders and the risk of injury. The aim of this study was to examine the association between patients with sleep disorders and the risk of injury.

METHODS

This was a population-based retrospective cohort study using Taiwan National Health Insurance Research Database from 2005 to 2010. A total of 15 109 patients with sleep disorders were identified as the study cohort. The non-sleep disorders control cohort comprised 29 955 age- and sex-matched patients. We conducted a Cox proportional hazard regression analysis to estimate the effects of sleep disorders on the risk of injury.

RESULTS

The overall incidence of injury was 77.03 per 1000 person-years for patients with sleep disorders, which was significantly higher than that of the control cohort (60.63 per 1000 person-years). Overall, patients with sleep disorders had a higher risk of injury compared with control cohort (adjusted HR=1.27, 95% CI 1.26 to 1.28). Comparing to the control cohort, patients with insomnia had a 12% higher risk for injury (adjusted HR, 1.12 (95% CI 1.01 to 1.41)).

CONCLUSIONS

Comparing to patients with non-sleep disorders, patients with sleep disorders had a higher risk of injury and the risk was particularly pronounced in those who had insomnia.

摘要

背景

睡眠障碍暴露与受伤风险之间的关联证据不足。本研究旨在探讨睡眠障碍患者与受伤风险之间的关联。

方法

这是一项基于人群的回顾性队列研究，使用了2005年至2010年的台湾国民健康保险研究数据库。共确定了15109名睡眠障碍患者作为研究队列。非睡眠障碍对照组包括29955名年龄和性别匹配的患者。我们进行了Cox比例风险回归分析，以估计睡眠障碍对受伤风险的影响。

结果

睡眠障碍患者的总体受伤发生率为每1000人年77.03例，显著高于对照组（每1000人年60.63例）。总体而言，睡眠障碍患者的受伤风险高于对照组（调整后HR=1.27，95%CI 1.26至1.28）。与对照组相比，失眠患者的受伤风险高12%（调整后HR，1.12（95%CI 1.01至1.41））。