Rooth Vera, van Oostrom Sandra H, Deeg Dorly J H, Verschuren W M Monique, Picavet H Susan J
National Institute for Public Health and the Environment-Centre for Nutrition, Prevention and Health Services, Bilthoven, The Netherlands.
VU University Medical Centre-Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, Amsterdam, The Netherlands.
Age Ageing. 2016 May;45(3):382-8. doi: 10.1093/ageing/afw018. Epub 2016 Feb 17.
to describe common trajectories of physical functioning and their determinants among an adult cohort, followed over a period of 15 years.
the study sample consisted of 4,123 participants (initial ages 26-70 years) from the Doetinchem Cohort Study, who participated in three or four measurement cycles. Physical functioning was measured with the Dutch version of the SF-36. Using a group-based modelling strategy, trajectories of physical functioning were determined. Weighted multinomial logistic regression analyses were performed to identify socio-demographic, lifestyle and health characteristics that differentiate between the trajectories at baseline.
five common physical functioning trajectories were distinguished, labelled as 'stable not limited' (27% of the population), 'stable slightly limited' (54%), 'slightly limited substantial deterioration' (7%), 'moderately limited gradual improvement' (9%) and 'stable severely limited' (3%). The characteristics that differentiate between the trajectories with limitations and the trajectory 'stable not limited' were being female, older, physically inactive, overweight or obese, having one or more chronic conditions, poor mental health and poor self-perceived health at baseline. Being younger, physically active, less obese, living with a partner and a good perceived health were characteristics of the trajectory 'moderately limited gradual improvement' compared with 'stable severely limited'.
five common trajectories of physical functioning were distinguished in an adult cohort, with most individuals following a stable but slightly limited course of physical functioning. Some early risk indicators were found that in the future might be used to early identify those with limitations in physical functioning.
描述成年队列中身体功能的常见轨迹及其决定因素,并对其进行为期15年的跟踪研究。
研究样本包括来自多廷赫姆队列研究的4123名参与者(初始年龄26 - 70岁),他们参加了三到四个测量周期。使用SF - 36荷兰语版本测量身体功能。采用基于群体的建模策略确定身体功能轨迹。进行加权多项逻辑回归分析,以识别在基线时区分不同轨迹的社会人口统计学、生活方式和健康特征。
区分出五种常见的身体功能轨迹,分别标记为“稳定无限制”(占人群的27%)、“稳定轻度受限”(54%)、“轻度受限显著恶化”(7%)、“中度受限逐渐改善”(9%)和“稳定严重受限”(3%)。与“稳定无限制”轨迹相比,有局限性的轨迹之间相互区分的特征包括女性、年龄较大、身体不活动、超重或肥胖、患有一种或多种慢性病、心理健康状况差以及基线时自我感知健康状况差。与“稳定严重受限”轨迹相比,“中度受限逐渐改善”轨迹的特征包括年龄较小、身体活跃、肥胖程度较低、与伴侣同住以及自我感知健康状况良好。
在一个成年队列中区分出了五种常见的身体功能轨迹,大多数个体的身体功能遵循稳定但略有受限的过程。发现了一些早期风险指标,未来可能用于早期识别身体功能有局限性的人群。