Tamaru C S, Kelley C D, Lee C S, Aida K, Hanyu I
Oceanic Institute, Honolulu, Hawaii 96825.
Gen Comp Endocrinol. 1989 Oct;76(1):114-27. doi: 10.1016/0016-6480(89)90038-5.
The striped mullet (Mugil cephalus) exhibits a restricted spawning season and matures only once per spawning cycle. In vivo monitoring of ovarian maturation of individual females during the season reveals that timing of full maturity varies. A small percentage of females that mature early can be induced to spawn and will remature. Such females can be spawned a second time within the same season. Chronic administration of luteinizing hormone-releasing analog (LHRH-a) + testosterone results in accelerated egg growth. The majority of females undergoing this therapy mature at least a month before control fish. When these females are induced to spawn, a higher percentage remature and can be spawned again. The double spawnings of both control and LHRH-a + testosterone-treated females occur without any appreciable loss in egg quality. Administration of LHRH-a + 17 alpha-methyltestosterone essentially inhibits egg growth. Steroid profiles from females undergoing this therapy exhibit a significant drop in circulating testosterone and estradiol 17 beta, compared to control and LHRH-a + testosterone-treated females. Hypotheses for the poor performance of this therapy are discussed.
条纹鲻（ Mugil cephalus）产卵季节有限，每个产卵周期仅成熟一次。在该季节对个体雌鱼的卵巢成熟进行体内监测发现，完全成熟的时间各不相同。一小部分早熟的雌鱼可以被诱导产卵并再次成熟。这类雌鱼可在同一季节内第二次产卵。长期施用促黄体生成激素释放类似物（LHRH-a）+睾酮可加速卵子生长。接受这种疗法的大多数雌鱼比对照鱼至少提前一个月成熟。当这些雌鱼被诱导产卵时，再次成熟并可再次产卵的比例更高。对照鱼和经LHRH-a +睾酮处理的雌鱼两次产卵时，卵子质量均无明显损失。施用LHRH-a + 17α-甲基睾酮基本上会抑制卵子生长。与对照鱼和经LHRH-a +睾酮处理的雌鱼相比，接受这种疗法的雌鱼的类固醇谱显示循环睾酮和雌二醇17β显著下降。文中讨论了这种疗法效果不佳的假设。
