Sutariya Harsh C, Pandya Vaidehi K
Assistant Professor, Department of Radio Diagnosis and Imaging, G. R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC)- Dr. H. L. Trivedi Institute of Transplantation Sciences (ITS) , Civil Hospital Campus, Asarwa, Ahmedabad, Gujarat, India .
Department of Radio Diagnosis and Imaging, G. R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre (IKDRC)- Dr. H. L. Trivedi Institute of Transplantation Sciences (ITS) , Civil Hospital Campus, Asarwa, Ahmedabad, Gujarat, India .
J Clin Diagn Res. 2016 Jan;10(1):TD10-2. doi: 10.7860/JCDR/2016/15092.7091. Epub 2016 Jan 1.
Renal Papillary Necrosis (RPN) is idefined as Ischemic necrobiosis of the papilla in the medulla of the kidneys. Variety of etiological factors are recognized which cause papillary necrosis, such as analgesic nephropathy, diabetes mellitus, urinary obstruction and sickle cell haemoglobinopathy. The early diagnosis of RPN is important to improve prognosis and reduce morbidity. Radiological Imaging offers early diagnosis and can guide prompt treatment of papillary necrosis and can minimize a decline in renal function. Here we report three cases of RPN with typical imaging findings. One of them was diabetic and hypertensive female with recurrent Urinary tract Infections and other was a male with no known co-morbidity. Both of them were diagnosed to have renal papillary necrosis on CT scan and were managed operatively and conservatively, respectively. Third case was a healthy female being investigated to be renal donor for her son. Here RPN was an incidental finding and was treated conservatively. Thus CT scan could detect it pre-operatively and complications due to transplantation of a kidney with papillary necrosis were avoided. So, we want to emphasize the importance of Radiology, particularly CT scanning in detection of RPN and to guide early and prompt treatment.
肾乳头坏死(RPN)被定义为肾髓质乳头的缺血性坏死。已认识到多种导致乳头坏死的病因,如镇痛剂肾病、糖尿病、尿路梗阻和镰状细胞血红蛋白病。RPN的早期诊断对于改善预后和降低发病率很重要。放射影像学可提供早期诊断,并能指导对乳头坏死的及时治疗,还可最大程度减少肾功能下降。在此我们报告3例具有典型影像学表现的RPN病例。其中1例是患有复发性尿路感染的糖尿病和高血压女性,另1例是无已知合并症的男性。他们两人经CT扫描均被诊断为肾乳头坏死,分别接受了手术治疗和保守治疗。第3例是一名健康女性,因其儿子而接受肾脏供体检查。在此,RPN是偶然发现的,并接受了保守治疗。因此,CT扫描能够在术前检测到它,避免了移植患有乳头坏死的肾脏所导致的并发症。所以,我们想强调放射学,尤其是CT扫描在检测RPN以及指导早期和及时治疗方面的重要性。