自身免疫性胰腺炎：诊断与管理的最新进展
Autoimmune Pancreatitis: An Update on Diagnosis and Management.
作者信息
Madhani Kamraan, Farrell James J
机构信息
Yale-Waterbury Internal Medicine Residency Program, Yale University School of Medicine, New Haven, CT 06510, USA.
Yale Center for Pancreatic Disease, Section of Digestive Disease, Yale University, LMP 1080, 15 York Street, New Haven, CT 06510, USA.
出版信息
Gastroenterol Clin North Am. 2016 Mar;45(1):29-43. doi: 10.1016/j.gtc.2015.10.005.
There is an evolving understanding that autoimmune pancreatitis (AIP) is an immunoglobulin (Ig) G4 systemic disease. It can manifest as primarily a pancreatic disorder or in association with other disorders of presumed autoimmune cause. Classic clinical characteristics include obstructive jaundice, abdominal pain, and acute pancreatitis. Thus, AIP can be difficult to distinguish from pancreatic malignancy. However, AIP may respond to therapy with corticosteroids, and has a strong association with other immune mediated diseases. Although primarily a pathologic diagnosis, attempts have been made to reliably diagnose AIP clinically. AIP can be classified as either type 1 or type 2.
人们逐渐认识到自身免疫性胰腺炎（AIP）是一种免疫球蛋白（Ig）G4系统性疾病。它可主要表现为胰腺疾病，或与其他推测由自身免疫引起的疾病相关。典型的临床特征包括梗阻性黄疸、腹痛和急性胰腺炎。因此，AIP可能难以与胰腺恶性肿瘤相区分。然而，AIP可能对皮质类固醇治疗有反应，并且与其他免疫介导的疾病有很强的关联。虽然AIP主要是一种病理诊断，但人们已尝试在临床上可靠地诊断AIP。AIP可分为1型或2型。
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