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原位肝移植后内脏利什曼病:一种罕见的感染原因。

Visceral leishmaniasis after orthotopic liver transplantation: a rare cause of infection.

作者信息

Pereira C M, Oliveira H M, Lopes V, Gandara J, Ferreira S, Daniel J, Miranda H P

机构信息

Hepato-pancreatic Transplantation Unit, Centro Hospitalar do Porto, Hospital de Santo António, Porto, Portugal.

Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal.

出版信息

Transpl Infect Dis. 2016 Apr;18(2):251-4. doi: 10.1111/tid.12511. Epub 2016 Mar 29.

Abstract

Visceral leishmaniasis (VL) was known as an opportunistic infection associated with immunosuppression, particularly related to human immunodeficiency virus infection and rarely to solid organ transplant recipients. We report a case of VL, 6 months after liver transplantation, in a patient who presented with febrile pancytopenia. The diagnosis was made by demonstration of amastigotes in smears from bone marrow. VL is a very rare infection in patients who undergo liver transplantation and, to our knowledge, this is the first case diagnosed in Portugal.

摘要

内脏利什曼病(VL)曾被认为是一种与免疫抑制相关的机会性感染,尤其与人类免疫缺陷病毒感染有关,在实体器官移植受者中很少见。我们报告一例肝移植6个月后发生VL的病例,该患者表现为发热性全血细胞减少。通过在骨髓涂片中发现无鞭毛体确诊。VL在肝移植患者中是一种非常罕见的感染,据我们所知,这是葡萄牙诊断的首例病例。

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