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完全腹腔镜活体供体右半肝切除术:中国大陆首例及文献综述

Total laparoscopic living donor right hemihepatectomy: first case in China mainland and literature review.

作者信息

Li Hongyu, Wei Yonggang, Li Bo

机构信息

Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan Province, China.

Department of Liver Surgery, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan Province, China.

出版信息

Surg Endosc. 2016 Oct;30(10):4622-3. doi: 10.1007/s00464-016-4750-z. Epub 2016 Feb 19.

Abstract

BACKGROUND

Total laparoscopic living donor right hemihepatectomy (LDRH) has been performed in several experienced transplant center [1-4]. We here report the first case of LDRH in China mainland and literature review.

METHODS

A 47-year-old man volunteered for living donation to his wife who suffered sclerosing cholangitis-related liver cirrhosis and hepatocellular carcinoma.

RESULTS

Donor height is 165 cm and weight is 65 kg, while the BMI is 23.9. Preoperative liver function tests were normal. The CT volume evaluation showed that the graft to body weight ratio (GBWR) was 1.42 % and the remnant liver volume was 36.3 % for right graft without middle hepatic vein. Biopsy result showed minimal steatosis. The anatomy of hepatic vein, artery, portal vein and bile duct was normal. A transection was performed along the cut line which was to the right side of middle hepatic vein. Two branches of the middle hepatic vein (Segment V and Segment VIII) were <5 mm in diameter, with no need of reconstruction. Hilar dissection was meticulously performed. Right portal vein, hepatic artery and bile duct were transected above the bifurcation. The right liver graft was placed in a retrieval bag and removed from suprapubic incision. The real graft volume was 660 ml with a revised GBWR of 1.14 %. Warm ischemia time was about 4 min. The postoperative course was uneventful for the donor. Literature review is shown in Table 1.

CONCLUSION

Total LDRH has been demonstrated technically feasible in selected adult donors. It may be a safe and minimally invasive option for adult donors in experienced transplant center.

摘要

背景

全腹腔镜活体供体右半肝切除术(LDRH)已在多个经验丰富的移植中心开展[1-4]。我们在此报告中国大陆首例LDRH病例并进行文献回顾。

方法

一名47岁男性自愿为患有硬化性胆管炎相关肝硬化和肝细胞癌的妻子进行活体供肝。

结果

供体身高165厘米,体重65千克,体重指数(BMI)为23.9。术前肝功能检查正常。CT容积评估显示,右半肝移植物(不含肝中静脉)的移植物与体重比(GBWR)为1.42%,残余肝体积为36.3%。活检结果显示脂肪变性轻微。肝静脉、肝动脉、门静脉和胆管的解剖结构正常。沿肝中静脉右侧的切割线进行横断。肝中静脉的两个分支(第V段和第VIII段)直径<5毫米,无需重建。仔细进行肝门解剖。在分叉上方切断右门静脉、肝动脉和胆管。将右肝移植物放入回收袋,经耻骨上切口取出。实际移植物体积为660毫升,修正后的GBWR为1.14%。热缺血时间约为4分钟。供体术后恢复顺利。文献回顾见表1。

结论

全腹腔镜活体供体右半肝切除术在选定的成年供体中已证明技术上可行。对于经验丰富的移植中心的成年供体而言,这可能是一种安全且微创的选择。

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