Konishi Yasunobu, Sakon Yoshito, Nakamura Ken, Fukunaga Naoto, Kanemitsu Hideo, Koyama Tadaaki
J Heart Valve Dis. 2015 May;24(3):383-5.
Osler's disease is a rare condition of autosomal dominant inheritance characterized by bleeding and telangiectasia of the skin and mucosal membranes. A few reports exist of open-heart surgery in patients with Osler's disease. Here, the case is presented of a successful pulmonary valvuloplasty using autologous pericardium to treat active infectious endocarditis of the pulmonary valve in a patient with Osler's disease. Such patients are at higher risk of bacteremia because of their chronic nasal bleeding or pulmonary arteriovenous fistula. In patients with Osler's disease, valuvloplasty using autologous pericardium is considered effective for preventing the later recurrence of IE.
奥斯勒病是一种罕见的常染色体显性遗传病，其特征为皮肤和黏膜出血及毛细血管扩张。有一些关于奥斯勒病患者接受心脏直视手术的报道。在此，本文介绍了一例使用自体心包成功进行肺动脉瓣成形术治疗奥斯勒病患者肺动脉瓣活动性感染性心内膜炎的病例。由于此类患者存在慢性鼻出血或肺动静脉瘘，发生菌血症的风险更高。对于奥斯勒病患者，使用自体心包进行瓣膜成形术被认为对预防感染性心内膜炎的后期复发有效。
