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挪威髋部骨折发病率持续下降:一项挪威骨质疏松症注册研究(NOREPOS研究)

Continued decline in hip fracture incidence in Norway: a NOREPOS study.

作者信息

Søgaard A J, Holvik K, Meyer H E, Tell G S, Gjesdal C G, Emaus N, Grimnes G, Schei B, Forsmo S, Omsland T K

机构信息

Norwegian Institute of Public Health, PO Box 4404, Nydalen, 0403, Oslo, Norway.

Institute of Health and Society, University of Oslo, 0318, Oslo, Norway.

出版信息

Osteoporos Int. 2016 Jul;27(7):2217-2222. doi: 10.1007/s00198-016-3516-8. Epub 2016 Feb 22.

Abstract

UNLABELLED

The previously reported decline in age-adjusted hip fracture rates in Norway during 1999-2008 continued after 2008. The annual number of hip fractures decreased in women and increased in men.

INTRODUCTION

Norway has among the highest hip fracture incidence rates ever reported despite previously observed declining rates from 1999 through 2008. The aim of the present study was to investigate whether this downward trend continued through 2013, and to compare gender-specific trends in 5 year age-groups during three time periods: 1999-2003, 2004-2008, and 2009-2013.

METHODS

All hip fractures (cervical, trochanteric, and sub-trochanteric) admitted to Norwegian hospitals were retrieved. Annual age-standardized incidence rates of hip fracture per 10,000 person-years by gender were calculated for the period 1999-2013. Time trends were tested by age-adjusted Poisson regression.

RESULTS

From 1999 through 2013 there were 140,136 hip fractures in persons aged 50 years and above. Age-adjusted hip fracture incidence rates declined by 20.4 % (95 % CI: 18.6-20.1) in women and 10.8 % (95 % CI: 7.8-13.8) in men, corresponding to an average annual age-adjusted decline of 1.5 % in women and 0.8 % in men. Except for the oldest men, hip fracture rates declined in all age-groups 70 years and older. The average annual number of fractures decreased in women (-0.3 %) and increased in men (+1.1 %).

CONCLUSIONS

During the past 15 years, hip fracture rates have declined in Norway. The forecasted growing number of older individuals might, however, cause an increase in the absolute number of fractures, with a substantial societal economic and public health burden.

摘要

未标注

挪威此前报告的1999 - 2008年期间年龄调整后的髋部骨折发生率下降情况在2008年后仍在持续。髋部骨折的年例数在女性中减少,在男性中增加。

引言

挪威曾是报告的髋部骨折发病率最高的国家之一,尽管此前观察到1999年至2008年发病率呈下降趋势。本研究的目的是调查这种下降趋势是否持续到2013年,并比较三个时间段(1999 - 2003年、2004 - 2008年和2009 - 2013年)中5岁年龄组的性别特异性趋势。

方法

检索挪威医院收治的所有髋部骨折(颈椎、转子和转子下)病例。计算1999 - 2013年期间按性别划分的每10000人年的年龄标准化髋部骨折发病率。通过年龄调整的泊松回归检验时间趋势。

结果

1999年至2013年期间,50岁及以上人群中有140136例髋部骨折。年龄调整后的髋部骨折发病率在女性中下降了20.4%(95%置信区间:18.6 - 20.1),在男性中下降了10.8%(95%置信区间:7.8 - 13.8),相当于女性平均每年年龄调整后下降1.5%,男性下降0.8%。除最年长的男性外,70岁及以上的所有年龄组髋部骨折发生率均下降。骨折的年平均例数在女性中减少(-0.3%),在男性中增加(+1.1%)。

结论

在过去15年中,挪威的髋部骨折发生率有所下降。然而,预计老年人口数量的增加可能会导致骨折绝对数量的增加,带来巨大的社会经济和公共卫生负担。

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