前白蛋白对重症坏死性小肠结肠炎的诊断价值
[Diagnostic value of prealbumin for severe necrotizing enterocolitis].
作者信息
Yang Yang, Pan Jing-Jing, Zhou Xiao-Yu, Zhou Xiao-Guang, Shen Xian
机构信息
Department of Neonatolgy, Nanjing Children′s Hospital of Nanjing Medical University, Nanjing 210008, China.
出版信息
Zhongguo Dang Dai Er Ke Za Zhi. 2016 Feb;18(2):105-7. doi: 10.7499/j.issn.1008-8830.2016.02.002.
OBJECTIVE
To study the clinical features of severe neonatal necrotizing enterocolitis (NEC), and to investigate the diagnostic value of prealbumin (PA) in neonates with severe NEC.
METHODS
The clinical data and results of routine blood test and blood biochemical test of 40 neonates with NEC (29 neonates with NEC II and 11 with NEC III) were analyzed. The multivariate logistic regression analysis and receiver operating characteristic (ROC) curve were applied to investigate the value of PA in the diagnosis of severe NEC.
RESULTS
The multivariate logistic regression analysis showed that PA was an important index for the diagnosis of severe NEC (≥IIB). The ROC analysis showed that in the diagnosis of severe NEC (≥IIB), PA had high sensitivity (0.870) and specificity (0.647).
CONCLUSIONS
PA has a good value in the diagnosis of severe NEC.
目的
研究重症新生儿坏死性小肠结肠炎（NEC）的临床特征，探讨前白蛋白（PA）在重症NEC新生儿中的诊断价值。
方法
分析40例NEC新生儿（29例NEC II期和11例NEC III期）的临床资料及血常规、血生化检查结果。采用多因素logistic回归分析和受试者工作特征（ROC）曲线探讨PA在重症NEC诊断中的价值。
结果
多因素logistic回归分析显示，PA是诊断重症NEC（≥IIB）的重要指标。ROC分析显示，在诊断重症NEC（≥IIB）时，PA具有较高的敏感性（0.870）和特异性（0.647）。
结论
PA在重症NEC的诊断中具有良好的价值。
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