Bennett J R
Hull Royal Infirmary, England.
Scand J Gastroenterol Suppl. 1989;165:59-61. doi: 10.3109/00365528909091232.
Cisapride has not been found to have a significant frequency of adverse reactions, except for diarrhoea which occurs in about 4% of individuals taking the drug. Cisapride is devoid of antidopaminergic effects (i.e. no neuro-endocrine effects such as prolactin increase; no extrapyramidal reactions). Clinical laboratory data show no effect of cisapride on haematology, blood chemistry, liver and kidney function. It is concluded that cisapride has a favourable safety profile.
除腹泻外，西沙必利未发现有显著不良反应发生率。腹泻约发生在4%服用该药的个体中。西沙必利无抗多巴胺能作用（即无神经内分泌作用，如催乳素升高；无锥体外系反应）。临床实验室数据表明西沙必利对血液学、血液化学、肝肾功能无影响。结论是西沙必利具有良好的安全性。
