Buiatti E, Palli D, Amadori D, Marubini E, Puntoni R, Avellini C, Bianchi S, Cipriani F, Cocco P, Decarli A
Centro per lo Studio e la Prevenzione Oncologica, Firenze, Italy.
Tumori. 1989 Oct 31;75(5):410-9. doi: 10.1177/030089168907500503.
The authors examine the problems of planning and conducting a multicentric case-control study on diet and gastric cancer in Italy. The solutions chosen for the study design, cases and controls identification, dietary interview, production of a common protocol for the field work are discussed. Results on the evaluation of the quality and comparability of collected data are presented. Further, compliance of cases and controls to the interview and to the blood and urine sampling with reasons of non-response are shown. Finally, the phases of the study and the methods for improving and controlling homogeneity among Centers are summarized.
作者们探讨了在意大利开展一项关于饮食与胃癌的多中心病例对照研究时所面临的规划和实施问题。讨论了在研究设计、病例与对照的识别、饮食访谈以及制定现场工作通用方案方面所采用的解决方案。展示了所收集数据的质量评估和可比性结果。此外，还呈现了病例和对照对访谈以及血液和尿液采样的依从性情况及无应答原因。最后，总结了研究阶段以及提高和控制各中心之间同质性的方法。
