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慢性阻塞性肺疾病急性加重期并发应激性心肌病

Stress Cardiomyopathy in the Setting of COPD Exacerbation.

作者信息

Landefeld Kevin, Saleh Qusai, Sander Gary E

机构信息

Tulane University School of Medicine, New Orleans, LA, USA.

出版信息

J Investig Med High Impact Case Rep. 2015 Oct 14;3(4):2324709615612847. doi: 10.1177/2324709615612847. eCollection 2015 Oct-Dec.

Abstract

Introduction. Stress cardiomyopathy, or takotsubo cardiomyopathy, is an acute, reversible left ventricular dysfunction usually initiated by a psychological or physical stress. We report this case of stress cardiomyopathy following a chronic obstructive pulmonary disease exacerbation and the subsequent treatment. Case Description. A 49-year-old white female with a history of chronic obstructive pulmonary disease presented to the emergency room via emergency medical services with worsening severe shortness of breath and productive cough for 2 weeks but denied any chest pain on arrival. On presentation, she was noted to be tachypneic, using her accessory muscles and with bilateral coarse expiratory wheezing on lung auscultation. Initial electrocardiogram demonstrated sinus tachycardia. She was treated with multiple albuterol treatments. Soon afterwards, the course was complicated by hypoxic respiratory failure eventually requiring intubation. Her repeat electrocardiogram showed acute changes consistent with myocardial infarction, and an echocardiograph demonstrated apical akinesia with an ejection fraction of 25% to 30%. The patient was urgently taken for cardiac catheterization, which showed no angiographic evidence of coronary artery disease. Three days after initial presentation, a repeat transthoracic echocardiogram showed overall left ventricular systolic function improvement. Discussion. This case provided a unique look at the difficulty of balancing catecholamines in a patient with bronchospasm and stress cardiomyopathy.

摘要

引言。应激性心肌病,即takotsubo心肌病,是一种急性、可逆的左心室功能障碍,通常由心理或身体应激引发。我们报告这例慢性阻塞性肺疾病急性加重及后续治疗后发生的应激性心肌病病例。病例描述。一名49岁有慢性阻塞性肺疾病病史的白人女性通过紧急医疗服务被送往急诊室,其严重气短和咳痰加重2周,但入院时否认有任何胸痛。就诊时,发现她呼吸急促,使用辅助呼吸肌,肺部听诊有双侧粗的呼气哮鸣音。初始心电图显示窦性心动过速。她接受了多次沙丁胺醇治疗。此后不久,病情因低氧性呼吸衰竭而复杂化,最终需要插管。她的复查心电图显示与心肌梗死一致的急性变化,超声心动图显示心尖运动减弱,射血分数为25%至30%。患者被紧急送去做心脏导管插入术,结果显示无冠状动脉疾病的血管造影证据。初次就诊三天后,复查经胸超声心动图显示左心室整体收缩功能改善。讨论。该病例为观察在患有支气管痉挛和应激性心肌病的患者中平衡儿茶酚胺的困难提供了独特视角。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2d4/4748508/a3fd3085a4b2/10.1177_2324709615612847-fig1.jpg

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