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基于单壁和多壁碳纳米管的药物递送系统:癌症治疗综述

Single-walled and multi-walled carbon nanotubes based drug delivery system: Cancer therapy: A review.

作者信息

Dineshkumar B, Krishnakumar K, Bhatt A R, Paul D, Cherian J, John A, Suresh S

机构信息

Department of Pharmaceutics, St James College of Pharmaceutical Sciences, Kerala, India.

出版信息

Indian J Cancer. 2015 Jul-Sep;52(3):262-4. doi: 10.4103/0019-509X.176720.

DOI:10.4103/0019-509X.176720
PMID:26905103
Abstract

Carbon nanotubes (CNTs) are advanced nano-carrier for delivery of drugs especially anti-cancer drugs. In the field of CNT-based drug delivery system, both single-walled carbon nanotubes (SWCNTs) and multi-walled nanotubes (MWCNTs) can be used for targeting anticancer drugs in tissues and organs, where the high therapeutic effect is necessary. Benefits of the carbon nanotubes (CNTs) in drug delivery systems are; avoiding solvent usage and reducing the side effects. Therefore, the present review article described about achievement of SWCNTs and MWCNTs to deliver the anticancer drugs with different cancerous cell lines.

摘要

碳纳米管(CNTs)是用于药物尤其是抗癌药物递送的先进纳米载体。在基于碳纳米管的药物递送系统领域,单壁碳纳米管(SWCNTs)和多壁碳纳米管(MWCNTs)均可用于在需要高治疗效果的组织和器官中靶向抗癌药物。碳纳米管(CNTs)在药物递送系统中的优势在于避免使用溶剂并减少副作用。因此,本综述文章描述了单壁碳纳米管和多壁碳纳米管在不同癌细胞系中递送抗癌药物方面的成果。

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