Issrani R, Ammanagi R, Keluskar V
Department of Oral Medicine and Radiology, Saraswati Medical and Dental College, Lucknow, Uttar Pradesh, India.
Indian J Cancer. 2015 Jul-Sep;52(3):370-4. doi: 10.4103/0019-509X.176724.
As oral physicians, we come across many oral mucosal lesions that usually require a supplementary biopsy with histopathologic examination to establish a definite diagnosis. The selection of the site for biopsy is the most important criteria to arrive at a correct diagnosis. As biopsy site is a subjective choice, it is possible that the biopsy specimens are taken from unrepresentative areas of the lesion. At present, though there are simple chair side methods to aid the diagnosis of such changes, there is a high risk of false positives. Hence, there is a need of a simple and reliable method for selecting the most appropriate area for biopsy. One such method is colposcopy that may be beneficial as compared to routine clinical examination. Hence, this article stresses on the colposcopic method that can be used to select biopsy sites which should be evaluated in further clinical studies.
作为口腔医生，我们会遇到许多口腔黏膜病变，通常需要进行补充活检并进行组织病理学检查以明确诊断。活检部位的选择是做出正确诊断的最重要标准。由于活检部位是主观选择，活检标本有可能取自病变的非代表性区域。目前，虽然有一些简单的椅旁方法有助于诊断此类变化，但假阳性风险很高。因此，需要一种简单可靠的方法来选择最合适的活检区域。一种这样的方法是阴道镜检查，与常规临床检查相比可能有益。因此，本文强调可用于选择活检部位的阴道镜检查方法，该方法应在进一步的临床研究中进行评估。
