Wolff Gillian F, Winters J Christian, Krlin Ryan M
Department of Urology, Louisiana State University Health Sciences Center, 1542 Tulane Avenue, New Orleans, LA, 70112, USA.
Curr Urol Rep. 2016 Apr;17(4):34. doi: 10.1007/s11934-016-0590-6.
Nearly 29% of women will undergo a secondary, repeat operation for pelvic organ prolapse (POP) symptom recurrence following a primary repair, as reported by Abbott et al. (Am J Obstet Gynecol 210:163.e1-163.e1, 2014). In efforts to decrease the rates of failure, graft materials have been utilized to augment transvaginal repairs. Following the success of using polypropylene mesh (PPM) for stress urinary incontinence (SUI), the use of PPM in the transvaginal repair of POP increased. However, in recent years, significant concerns have been raised about the safety of PPM mesh. Complications, some specific to mesh, such as exposures, erosion, dyspareunia, and pelvic pain, have been reported with increased frequency. In the current literature, there is not substantive evidence to suggest that PPM has intrinsic properties that warrant total mesh removal in the absence of complications. There are a number of complications that can occur after transvaginal mesh placement that do warrant surgical intervention after failure of conservative therapy. In aggregate, there are no high-quality controlled studies that clearly demonstrate that total mesh removal is consistently more likely to achieve pain reduction. In the cases of obstruction and erosion, it seems clear that definitive removal of the offending mesh is associated with resolution of symptoms in the majority of cases and reasonable practice. There are a number of complications that can occur with removal of mesh, and patients should be informed of this as they formulate a choice of treatment. We will review these considerations as we examine the clinical question of whether total versus partial removal of mesh is necessary for the resolution of complications following transvaginal mesh placement.
雅培等人报告称(《美国妇产科杂志》210:163.e1 - 163.e1,2014),近29%的女性在初次修复盆腔器官脱垂(POP)后,会因症状复发而接受二次重复性手术。为降低失败率,人们使用了移植材料来加强经阴道修复。在聚丙烯网片(PPM)用于治疗压力性尿失禁(SUI)取得成功后,PPM在经阴道修复POP中的使用增加。然而,近年来,人们对PPM网片的安全性提出了重大担忧。已报告出现了一些并发症,其中一些是网片特有的,如暴露、侵蚀、性交困难和盆腔疼痛,且频率有所增加。在当前文献中,没有实质性证据表明PPM具有在无并发症情况下需要完全取出网片的内在特性。经阴道放置网片后可能会出现一些并发症,在保守治疗失败后确实需要手术干预。总体而言,没有高质量的对照研究能清楚地表明完全取出网片始终更有可能减轻疼痛。在梗阻和侵蚀的情况下,显然在大多数病例中明确取出有问题的网片与症状缓解及合理做法相关。取出网片可能会出现一些并发症,在患者做出治疗选择时应告知他们这一点。在探讨经阴道放置网片后,对于解决并发症而言,完全取出网片还是部分取出网片是否必要这一临床问题时,我们将审视这些考虑因素。