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自噬受到攻击。

Autophagy under attack.

作者信息

de Figueiredo Paul, Dickman Marty

机构信息

Norman Borlaug Institute, Department of Veterinary Pathobiology and Department of Microbial Pathogenesis and Immunology, Texas A&M University, College Station, United States.

Norman Borlaug Institute and the Department of Plant Pathology and Microbiology, Texas A&M University, College Station, United States.

出版信息

Elife. 2016 Feb 23;5:e14447. doi: 10.7554/eLife.14447.

DOI:10.7554/eLife.14447
PMID:26906167
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4775212/
Abstract

Pathogens target proteins involved in autophagy to inhibit immune responses in plants.

摘要

病原体靶向自噬相关蛋白以抑制植物的免疫反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58ca/4775212/e5ab214efddb/elife-14447-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58ca/4775212/e5ab214efddb/elife-14447-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58ca/4775212/e5ab214efddb/elife-14447-fig1.jpg

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Re-emergence of Potato and Tomato Late Blight in the United States.马铃薯和番茄晚疫病在美国再度出现。
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An effector of the Irish potato famine pathogen antagonizes a host autophagy cargo receptor.爱尔兰马铃薯饥荒病原体的一种效应蛋白拮抗宿主自噬货物受体。
Elife. 2016 Jan 14;5:e10856. doi: 10.7554/eLife.10856.
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The Legionella Anti-autophagy Effector RavZ Targets the Autophagosome via PI3P- and Curvature-Sensing Motifs.军团菌抗自噬效应因子 RavZ 通过 PI3P 和弯曲感知基序靶向自噬体。
γb Protein Subverts Autophagy to Promote Viral Infection by Disrupting the ATG7-ATG8 Interaction.
γb 蛋白通过破坏 ATG7-ATG8 相互作用来颠覆自噬以促进病毒感染。
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Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration.1型人类免疫缺陷病毒Nef蛋白通过隔离转录因子EB抑制自噬。
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A screen of Coxiella burnetii mutants reveals important roles for Dot/Icm effectors and host autophagy in vacuole biogenesis.对伯纳特柯克斯体突变体的筛选揭示了Dot/Icm效应蛋白和宿主自噬在液泡生物发生中的重要作用。
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Filamentous pathogen effector functions: of pathogens, hosts and microbiomes.丝状病原体效应子功能：病原体、宿主与微生物群落
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Cargo recognition and trafficking in selective autophagy.货物识别与选择性自噬中的物质运输。
Nat Cell Biol. 2014 Jun;16(6):495-501. doi: 10.1038/ncb2979.
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The Fusarium oxysporum effector Six6 contributes to virulence and suppresses I-2-mediated cell death.尖孢镰刀菌效应因子 Six6 有助于致病力并抑制 I-2 介导体细胞死亡。
Mol Plant Microbe Interact. 2014 Apr;27(4):336-48. doi: 10.1094/MPMI-11-13-0330-R.
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The autophagosome: origins unknown, biogenesis complex.自噬体：来源不明，生物发生复杂。
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The pore-forming bacterial effector, VopQ, halts autophagic turnover.细菌效应蛋白 VopQ 形成孔道，从而阻止自噬体的降解。
Autophagy. 2013 Dec;9(12):2169-70. doi: 10.4161/auto.26449. Epub 2013 Oct 8.