Agrba V Z, Porkhanov V A, Karal-Ogly D D, Leontyuk A V, Kovalenko A L, Sholin I Yu, Gvozdik T E, Ignatova I E, Agumava A A, Chuguev Yu P, Gvaramiya I A, Lapin B A
Research Institute of Medical Primatology, Sochi, Russia.
Bull Exp Biol Med. 2016 Feb;160(4):589-91. doi: 10.1007/s10517-016-3223-7. Epub 2016 Feb 24.
Culture of mesenchymal stem cells isolated from the bone marrow of primates by their characteristics met the requirements of stem cells. It was shown that transplantation of allogeneic mesenchymal stem cells (2 million cells per 1 kg body weight) immediately after ligation of the left anterior descending coronary artery between the middle and upper thirds led to neovascularization and capillarization of the ischemic myocardium.
从灵长类动物骨髓中分离出的间充质干细胞,经鉴定其特性符合干细胞要求。研究表明,在左前降支冠状动脉中上部三分之一处结扎后立即移植异体间充质干细胞(每1千克体重移植200万个细胞),可使缺血心肌实现新血管形成和毛细血管化。