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[现代二尖瓣手术]

[Modern mitral valve surgery].

作者信息

Bothe W, Beyersdorf F

机构信息

Klinik für Herz-und Gefäßchirurgie, Universitäts-Herzzentrum Freiburg - Bad Krozingen, Hugstetter Str. 55, 79106, Freiburg, Deutschland.

出版信息

Internist (Berl). 2016 Apr;57(4):332-40. doi: 10.1007/s00108-016-0032-z.

DOI:10.1007/s00108-016-0032-z
PMID:26907868
Abstract

At the beginning of the 20th century, Cutler and Levine performed the first successful surgical treatment of a stenotic mitral valve, which was the only treatable heart valve defect at that time. Mitral valve surgery has evolved significantly since then. The introduction of the heart-lung machine in 1954 not only reduced the surgical risk, but also allowed the treatment of different mitral valve pathologies. Nowadays, mitral valve insufficiency has become the most common underlying pathomechanism of mitral valve disease and can be classified into primary and secondary mitral insufficiency. Primary mitral valve insufficiency is mainly caused by alterations of the valve (leaflets and primary order chords) itself, whereas left ventricular dilatation leading to papillary muscle displacement and leaflet tethering via second order chords is the main underlying pathomechanism for secondary mitral valve regurgitation. Valve reconstruction using the "loop technique" plus annuloplasty is the surgical strategy of choice and normalizes life expectancy in patients with primary mitral regurgitation. In patients with secondary mitral regurgitation, implanting an annuloplasty is not superior to valve replacement and results in high rates of valve re-insufficiency (up to 30 % after 3 months) due to ongoing ventricular dilatation. In order to improve repair results in these patients, we add a novel subvalvular technique (ring-noose-string) to the annuloplasty that aims to prevent ongoing ventricular remodeling and re-insufficiency. In modern mitral surgery, a right lateral thoracotomy is the approach of choice with excellent repair and cosmetic results.

摘要

20世纪初,卡特勒和莱文首次成功实施了二尖瓣狭窄的外科治疗,这是当时唯一可治疗的心脏瓣膜缺陷。从那时起,二尖瓣手术有了显著发展。1954年心肺机的引入不仅降低了手术风险,还使得不同的二尖瓣病变能够得到治疗。如今,二尖瓣关闭不全已成为二尖瓣疾病最常见的潜在病理机制,可分为原发性和继发性二尖瓣关闭不全。原发性二尖瓣关闭不全主要由瓣膜(瓣叶和一级腱索)本身的改变引起,而左心室扩张导致乳头肌移位以及通过二级腱索使瓣叶受限是继发性二尖瓣反流的主要潜在病理机制。采用“环路技术”加瓣环成形术进行瓣膜重建是原发性二尖瓣反流患者的首选手术策略,可使患者预期寿命正常化。在继发性二尖瓣反流患者中,植入瓣环成形术并不优于瓣膜置换术,并且由于心室持续扩张,瓣膜再次关闭不全的发生率较高(3个月后高达30%)。为了改善这些患者的修复效果,我们在瓣环成形术中增加了一种新型的瓣下技术(环套索),旨在防止心室持续重塑和再次关闭不全。在现代二尖瓣手术中,右外侧开胸术是首选方法,修复效果和美容效果都非常好。

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引用本文的文献

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本文引用的文献

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Left ventricular performance early after repair for posterior mitral leaflet prolapse: Chordal replacement versus leaflet resection.二尖瓣后叶脱垂修复术后早期左心室功能:腱索置换与瓣叶切除。
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Ring-Noose-String Technique Allows Adjustable Papillary Muscle Repositioning During Minimally Invasive Mitral Valve Repair in Patients with Functional/Ischemic Mitral Regurgitation.环套索线技术可在功能性/缺血性二尖瓣反流患者的微创二尖瓣修复术中实现可调节的乳头肌重新定位。
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Mitral-valve repair versus replacement for severe ischemic mitral regurgitation.
二尖瓣修复与置换治疗严重缺血性二尖瓣反流。
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Minimally invasive mitral valve surgery is a very safe procedure with very low rates of conversion to full sternotomy.微创二尖瓣手术是一种非常安全的手术,转为全胸骨切开术的比例非常低。
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THE SURGICAL TREATMENT OF MITRAL STENOSIS.二尖瓣狭窄的外科治疗
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RING+STRING: Successful repair technique for ischemic mitral regurgitation with severe leaflet tethering.RING+STRING:用于严重瓣叶牵拉的缺血性二尖瓣反流的成功修复技术。
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Long-term survival in asymptomatic patients with severe degenerative mitral regurgitation: a propensity score-based comparison between an early surgical strategy and a conservative treatment approach.无症状重度退行性二尖瓣反流患者的长期生存:早期手术策略与保守治疗方法的倾向评分比较
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Comparison of outcomes of minimally invasive mitral valve surgery for posterior, anterior and bileaflet prolapse.比较微创二尖瓣手术治疗后瓣叶、前瓣叶和双瓣叶脱垂的疗效。
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