Bothe W, Beyersdorf F
Klinik für Herz-und Gefäßchirurgie, Universitäts-Herzzentrum Freiburg - Bad Krozingen, Hugstetter Str. 55, 79106, Freiburg, Deutschland.
Internist (Berl). 2016 Apr;57(4):332-40. doi: 10.1007/s00108-016-0032-z.
At the beginning of the 20th century, Cutler and Levine performed the first successful surgical treatment of a stenotic mitral valve, which was the only treatable heart valve defect at that time. Mitral valve surgery has evolved significantly since then. The introduction of the heart-lung machine in 1954 not only reduced the surgical risk, but also allowed the treatment of different mitral valve pathologies. Nowadays, mitral valve insufficiency has become the most common underlying pathomechanism of mitral valve disease and can be classified into primary and secondary mitral insufficiency. Primary mitral valve insufficiency is mainly caused by alterations of the valve (leaflets and primary order chords) itself, whereas left ventricular dilatation leading to papillary muscle displacement and leaflet tethering via second order chords is the main underlying pathomechanism for secondary mitral valve regurgitation. Valve reconstruction using the "loop technique" plus annuloplasty is the surgical strategy of choice and normalizes life expectancy in patients with primary mitral regurgitation. In patients with secondary mitral regurgitation, implanting an annuloplasty is not superior to valve replacement and results in high rates of valve re-insufficiency (up to 30 % after 3 months) due to ongoing ventricular dilatation. In order to improve repair results in these patients, we add a novel subvalvular technique (ring-noose-string) to the annuloplasty that aims to prevent ongoing ventricular remodeling and re-insufficiency. In modern mitral surgery, a right lateral thoracotomy is the approach of choice with excellent repair and cosmetic results.
20世纪初,卡特勒和莱文首次成功实施了二尖瓣狭窄的外科治疗,这是当时唯一可治疗的心脏瓣膜缺陷。从那时起,二尖瓣手术有了显著发展。1954年心肺机的引入不仅降低了手术风险,还使得不同的二尖瓣病变能够得到治疗。如今,二尖瓣关闭不全已成为二尖瓣疾病最常见的潜在病理机制,可分为原发性和继发性二尖瓣关闭不全。原发性二尖瓣关闭不全主要由瓣膜(瓣叶和一级腱索)本身的改变引起,而左心室扩张导致乳头肌移位以及通过二级腱索使瓣叶受限是继发性二尖瓣反流的主要潜在病理机制。采用“环路技术”加瓣环成形术进行瓣膜重建是原发性二尖瓣反流患者的首选手术策略,可使患者预期寿命正常化。在继发性二尖瓣反流患者中,植入瓣环成形术并不优于瓣膜置换术,并且由于心室持续扩张,瓣膜再次关闭不全的发生率较高(3个月后高达30%)。为了改善这些患者的修复效果,我们在瓣环成形术中增加了一种新型的瓣下技术(环套索),旨在防止心室持续重塑和再次关闭不全。在现代二尖瓣手术中,右外侧开胸术是首选方法,修复效果和美容效果都非常好。