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免疫功能正常宿主的皮肤曲霉病表现:前臂肿块病变的罕见表现。

A manifestation of cutaneous aspergillosis in immunocompetent host: A rare presentation as forearm mass lesion.

机构信息

Department of Orthopaedics, IMS and SUM Hospital, Siksha 'O' Anusandhan University, K-8, Kalinga Nagar, Bhubaneswar, 751003, Odisha, India.

Department of Orthopaedics, IMS and SUM Hospital, Siksha 'O' Anusandhan University, K-8, Kalinga Nagar, Bhubaneswar, 751003, Odisha, India.

出版信息

J Mycol Med. 2016 Mar;26(1):51-5. doi: 10.1016/j.mycmed.2015.12.009. Epub 2016 Feb 18.

Abstract

The Aspergillus species is a ubiquitous fungus, which can cause pathogenic and opportunistic fungal infections in the immunocompromised. This is an atypical occurrence in the host with an otherwise normal immune status. We report a case of an immunocompetent 45-year-old patient who developed cutaneous aspergillosis with a very benign course presenting simply with a gradually enlarging mass and none of the classical signs and symptoms. All prior laboratory examinations failed to detect or reproduce the organism or establish a diagnosis. Surgery was both diagnostic and therapeutic, to remove the mass which causes the patient pain and limitation of activity. This was to our advantage because the fungal elements were very well encapsulated and the mass was a well-organized conglomeration of cystic abscesses that even prolonged chemotherapy alone might not succeed in eradicating the infection.

摘要

烟曲霉是一种无处不在的真菌,可导致免疫功能低下者发生致病性和机会性真菌感染。在免疫功能正常的宿主中,这种情况并不常见。我们报告了一例免疫功能正常的 45 岁患者,他患有皮肤曲霉病,病程非常良性,仅表现为逐渐增大的肿块,没有任何典型的体征和症状。所有先前的实验室检查都未能检测或重现该病原体,也未能确诊。手术既是诊断也是治疗,可以切除导致患者疼痛和活动受限的肿块。这对我们有利,因为真菌成分被很好地包裹,肿块是囊性脓肿的良好组合,即使单独延长化疗也可能无法成功消除感染。

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