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Primary cutaneous aspergillosis due to Aspergillus niger in an immunocompetent patient.免疫功能正常患者发生由黑曲霉引起的原发性皮肤曲霉病。
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免疫功能正常宿主中由塔宾曲霉引起的原发性皮肤曲霉病。

Primary cutaneous aspergillosis due to Aspergillus tamarii in an immunocompetent host.

作者信息

Sharma Sadhna, Yenigalla Bindu Madhav, Naidu Sujeet Kumar, Pidakala Premalatha

机构信息

Department of Internal Medicine, NRI Medical College, Mangalagiri, Andhra Pradesh, India.

出版信息

BMJ Case Rep. 2013 Aug 22;2013:010128. doi: 10.1136/bcr-2013-010128.

DOI:10.1136/bcr-2013-010128
PMID:23970496
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3761659/
Abstract

Primary cutaneous aspergillosis is a rare disease usually caused by Aspergillus fumigatus, Aspergillus flavus, Aspergillus terreus and Aspergillus ustus. It is usually seen in immunocompromised hosts, though some cases are also reported in immunocompetent hosts. We present a case of an immunocompetent farmer who presented with generalised nodules and plaques, mimicking erythema nodosum leprosum but turned out to be cutaneous aspergillosis caused by Aspergillus tamarii. The characteristic ascospores of Aspergillus species were found in skin lesions on fungus isolated in culture. The patient showed excellent response to antifungal therapy.

摘要

原发性皮肤曲霉病是一种罕见疾病，通常由烟曲霉、黄曲霉、土曲霉和黑曲霉引起。该病常见于免疫功能低下的宿主，不过也有一些病例报告发生在免疫功能正常的宿主中。我们报告一例免疫功能正常的农民病例，该患者表现为全身性结节和斑块，类似瘤型麻风的结节性红斑，但最终确诊为由塔宾曲霉引起的皮肤曲霉病。在培养分离出的真菌中，皮肤病变处发现了曲霉菌种特有的子囊孢子。该患者对抗真菌治疗反应良好。