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极低出生体重成人同伴受害的长期精神影响。

Long-term Psychiatric Impact of Peer Victimization in Adults Born at Extremely Low Birth Weight.

作者信息

Day Kimberly L, Schmidt Louis A, Vaillancourt Tracy, Saigal Saroj, Boyle Michael H, Van Lieshout Ryan J

机构信息

Departments of Psychiatry and Behavioural Neurosciences,

Psychology, Neuroscience & Behaviour, and.

出版信息

Pediatrics. 2016 Mar;137(3):e20153383. doi: 10.1542/peds.2015-3383. Epub 2016 Feb 17.

Abstract

BACKGROUND

While children born at extremely low birth weight (ELBW; <1000 g) are at elevated risk for peer victimization, no research has examined its effects on mental health in adulthood.

METHODS

ELBW survivors and matched normal birth weight (NBW; >2500 g) controls were part of a prospective, population-based study in Ontario, Canada. Peer victimization before age 16 was self-reported at age 22 to 26 years by using a 10-point measure. Presence of psychiatric disorders was examined at age 22 to 26 years (ELBW n = 142, NBW n = 133) and age 29 to 36 years (ELBW n = 84, NBW n = 90).

RESULTS

After adjustment for confounding variables, for each 1-point increase in the peer victimization score, ELBW survivors had increased odds of current depressive (odds ratio [OR] = 1.67, 95% confidence interval [CI], 1.23-2.28), anxiety (OR = 1.36, 95% CI, 1.05-1.76), avoidant (OR = 1.39, 95% CI, 1.08-1.79), antisocial (OR = 1.92, 95% CI, 1.06-2.87), and attention-deficit/hyperactivity (OR = 1.39, 95% CI, 1.06-1.83) problems at age 22 to 26 years. At age 29 to 36 years, peer victimization score predicted increased odds of current panic disorder (OR = 1.69, 95% CI, 1.01-2.83) and obsessive-compulsive disorder (OR = 3.56, 95% CI, 1.25-10.09). For NBW controls, peer victimization predicted increased odds of antisocial problems at age 22 to 26 years.

CONCLUSIONS

ELBW survivorsand NBW participants are vulnerable to the adverse psychiatric effects of childhood peer victimization in adulthood.

摘要

背景

出生时体重极低(ELBW;<1000克)的儿童遭受同伴欺侮的风险较高,但尚无研究考察其对成年后心理健康的影响。

方法

ELBW幸存者和匹配的正常出生体重(NBW;>2500克)对照者是加拿大安大略省一项基于人群的前瞻性研究的一部分。16岁之前的同伴欺侮情况在22至26岁时通过10分制自我报告。在22至26岁(ELBW组n = 142,NBW组n = 133)和29至36岁(ELBW组n = 84,NBW组n = 90)时检查精神障碍的存在情况。

结果

在对混杂变量进行调整后,同伴欺侮得分每增加1分,ELBW幸存者在22至26岁时出现当前抑郁(优势比[OR]=1.67,95%置信区间[CI],1.23 - 2.28)、焦虑(OR = 1.36,95%CI,1.05 - 1.76)、回避型(OR = 1.39,95%CI,1.08 - 1.79)、反社会(OR = 1.92,95%CI,1.06 - 2.87)以及注意力缺陷/多动(OR = 1.39,95%CI,1.06 - 1.83)问题的几率增加。在29至36岁时,同伴欺侮得分预示当前惊恐障碍(OR = 1.69,95%CI,1.01 - 2.83)和强迫症(OR = 3.56,95%CI,1.25 - 10.09)的几率增加。对于NBW对照者,同伴欺侮预示在22至26岁时反社会问题的几率增加。

结论

ELBW幸存者和NBW参与者在成年期易受童年同伴欺侮的不良精神影响。

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