Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada.
Department of Psychology, Neuroscience & Behaviour, McMaster University, Hamilton, Ontario, Canada.
Sleep Med. 2019 Jan;53:28-34. doi: 10.1016/j.sleep.2018.09.007. Epub 2018 Sep 29.
To examine associations between parent-reported child sleep walking or talking, nightmares, and trouble sleeping at age eight and psychiatric problems in adulthood (age 30-35) in extremely low birth weight (ELBW; <1000 g) survivors and matched normal birth weight (NBW; >2500 g) control participants.
At age eight, parents of ELBW survivors and NBW control participants completed sleep items on the Child Behavior Checklist assessing the presence of sleep walking/talking, nightmares, or trouble sleeping. At age 30-35, 98 ELBW and 94 NBW individuals completed the Mini International Neuropsychiatric Interview (MINI), Beck Anxiety Inventory (BAI), and Beck Depression Inventory (BDI). Analyses were conducted in each birth weight group independently.
In NBW participants, sleep walking/talking in childhood predicted higher BAI and BDI scores, as well as more than three times the odds of having a mood or anxiety disorder (OR = 3.48; 95% CI, 1.26-9.60) at age 30-35. Sex and childhood sleep problem interactions revealed that females who manifested sleep walking/talking as children had higher BAI scores than males. Nightmares in children born at NBW predicted higher BAI scores. These associations persisted despite adjustment for child mental health, sex, socioeconomic status, sexual or physical abuse, and family functioning. Trouble sleeping in childhood did not predict adult mental health problems. Childhood sleep problems did not predict psychopathology in ELBW adults.
Children born at NBW who manifest sleep walking or talking appear to be at increased risk for developing mood or anxiety disorders in adulthood. No associations between child sleep and adult mental illness were noted in those with ELBW surviviors. Childhood sleep walking/talking may be a unique risk factor for mental health problems later in life.
研究 8 岁时父母报告的儿童梦游、说梦话和睡眠问题与极低出生体重（ELBW；<1000 克）幸存者和匹配的正常出生体重（NBW；>2500 克）对照组成年后（30-35 岁）精神问题之间的关联。
在 8 岁时，ELBW 幸存者和 NBW 对照组的父母完成了儿童行为检查表中的睡眠项目，评估是否存在梦游/说梦话、噩梦或睡眠问题。在 30-35 岁时，98 名 ELBW 和 94 名 NBW 个体完成了迷你国际神经精神访谈（MINI）、贝克焦虑量表（BAI）和贝克抑郁量表（BDI）。在每个出生体重组中独立进行分析。
在 NBW 参与者中，儿童期的梦游/说梦话预示着更高的 BAI 和 BDI 评分，以及超过三倍的情绪或焦虑障碍（OR=3.48；95%CI，1.26-9.60）的几率。性别和儿童睡眠问题的相互作用表明，儿童期出现梦游/说梦话的女性的 BAI 评分高于男性。NBW 出生的儿童的噩梦预示着更高的 BAI 评分。这些关联在调整儿童心理健康、性别、社会经济地位、性或身体虐待以及家庭功能后仍然存在。儿童期的睡眠问题并不能预测成年后的心理健康问题。儿童期的睡眠问题并不能预测 ELBW 成人的精神病理学。
NBW 出生的表现出梦游或说梦话的儿童似乎在成年后患情绪或焦虑障碍的风险增加。在 ELBW 幸存者中，儿童睡眠与成年精神疾病之间没有关联。儿童期的梦游/说梦话可能是成年后心理健康问题的一个独特危险因素。
