Aslam Moaz, Aleem Numra A, Zahid Mohammad F, Rahman Arshalooz J
Medical College, Aga Khan University, Karachi, Pakistan.
Department of Pediatrics & Child Health, Aga Khan University, Karachi, Pakistan.
Sultan Qaboos Univ Med J. 2016 Feb;16(1):e101-4. doi: 10.18295/squmj.2016.16.01.019. Epub 2016 Feb 2.
Dengue fever (DF) is an acute febrile illness that follows a self-limiting course. However, some patients suffer from complications, including myocarditis, due to the involvement of other organs. A child presented at the Aga Khan University Hospital in Karachi, Pakistan, in June 2013 with a high-grade fever, malaise and epigastric pain radiating to the chest. Positive DF antigen and immunoglobulin M assays confirmed the diagnosis of DF. Persistent bradycardia with low blood pressure led to further cardiac investigations which showed a decreased ejection fraction and raised serum cardiac enzymes, indicating myocardial damage. With supportive care and use of inotropes, the spontaneous normalisation of cardiac enzyme levels and ejection fraction was observed. The child was discharged five days after admission. This case highlights the importance of identifying myocarditis in DF patients suffering from cardiac symptoms that are not explained by other potential aetiologies. Awareness, early suspicion and supportive care are essential to ensure favourable outcomes.
登革热(DF)是一种呈自限性病程的急性发热性疾病。然而,一些患者会出现并发症,包括因其他器官受累而引发的心肌炎。2013年6月,一名儿童在巴基斯坦卡拉奇的阿迦汗大学医院就诊,伴有高热、不适以及放射至胸部的上腹部疼痛。登革热抗原和免疫球蛋白M检测呈阳性,确诊为登革热。持续性心动过缓伴低血压促使进一步进行心脏检查,结果显示射血分数降低且血清心肌酶升高,提示心肌损伤。通过支持治疗和使用正性肌力药物,观察到心肌酶水平和射血分数自发恢复正常。患儿入院五天后出院。该病例凸显了在登革热患者中识别心肌炎的重要性,这些患者出现的心脏症状无法用其他潜在病因解释。提高认识、早期怀疑并给予支持治疗对于确保良好预后至关重要。