Animal and Plant Sciences, University of Sheffield, Sheffield, UK.
Public Health. 2013 Jan;127(1):11-7. doi: 10.1016/j.puhe.2012.09.006. Epub 2012 Dec 6.
The presence of dengue virus has been detected using neutralization and haemagglutination inhibition antibodies in local populations in Pakistan since the 1960s. However, the first epidemic was not reported until 1994. This was followed by some cases in 1995, but the disease was confined to the port city of Karachi. Since 2006, dengue epidemics have occurred every year and the range has extended to most cities in Pakistan. Dengue now affects thousands of people and has caused hundreds of deaths. It has become a major health problem in Pakistan, and it is likely to become an even greater health problem in the coming years. This review gives an insight into the dengue situation from the early 1960s to the most recent epidemics in Pakistan, and also describes the primary vector of this disease (Aedes aegypti) in Pakistan. As such, it provides the first comprehensive review of the emergence of this important public health problem.
自 20 世纪 60 年代以来，巴基斯坦当地人群中已使用中和及血凝抑制抗体检测到登革热病毒的存在。然而，直到 1994 年才首次报告出现疫情。随后，1995 年出现了一些病例，但该疾病仅限于港口城市卡拉奇。自 2006 年以来，登革热疫情每年都发生，疫情范围已扩大到巴基斯坦的大多数城市。登革热现在影响了数千人，并导致数百人死亡。它已成为巴基斯坦的一个主要卫生问题，并且在未来几年内很可能成为一个更大的卫生问题。这篇综述深入探讨了从 20 世纪 60 年代初到巴基斯坦最近的登革热疫情的情况，并描述了该疾病在巴基斯坦的主要传播媒介（埃及伊蚊）。因此，它首次全面审查了这一重要公共卫生问题的出现。
