意大利骨转移管理横断面调查：ZeTa研究。
The Italian cross-sectional survey of the management of bone metastasis: ZeTa study.
作者信息
Santini Daniele, Bertoldo Francesco, Dell'Aquila Emanuela, Cecchini Isabella, Fregosi Stefania, Bortolussi Paolo
机构信息
Oncologia Medica, University Campus Biomedico, Roma, Rome, Italy.
Department of Medicine, University of Verona, Verona, Italy.
出版信息
J Bone Oncol. 2012 Jul 21;1(2):35-9. doi: 10.1016/j.jbo.2012.04.005. eCollection 2012 Sep.
BACKGROUND
Several studies have emphasized the importance of the maintenance of bone health in a comprehensive cancer care. However, no survey about approach to bone metastasis care is currently available. The ZeTa study provides a picture of the Italian oncologists' therapeutics habits in this area, in a real clinical-practice scenario.
DESIGN
This study was based on online questionnaire-based interviews to Italian oncologists that included 145 questions. The aim was to collect information on the treatment of bone metastasis, the current use of bisphosphonates, the awareness of guidelines and the concerns about ONJ, the use of vitamin D supplementation.
RESULTS
445 oncologists were contacted, 283 agreed to participate. The results show that the current management of bone metastasis is still sub-optimal, as the recommendations from current clinical guidelines are not completely followed by all specialists.
CONCLUSIONS
This survey highlights the urgent need to improve management of bone metastasis in cancer patients.
背景
多项研究强调了在综合癌症护理中维持骨骼健康的重要性。然而，目前尚无关于骨转移护理方法的调查。泽塔研究呈现了意大利肿瘤学家在这一领域真实临床实践中的治疗习惯。
设计
本研究基于对意大利肿瘤学家进行的在线问卷调查访谈，问卷包含145个问题。目的是收集有关骨转移治疗、双膦酸盐的当前使用情况、对指南的认识以及对颌骨坏死的担忧、维生素D补充剂的使用等方面的信息。
结果
联系了445名肿瘤学家，283名同意参与。结果表明，目前骨转移的管理仍不理想，因为并非所有专家都完全遵循当前临床指南的建议。
结论
这项调查凸显了迫切需要改善癌症患者骨转移的管理。
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