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18F-NaF PET/CT 检测到源于骨肉瘤的肿瘤血栓的罕见表现。

Unusual Finding of a Tumor Thrombus Arising From Osteosarcoma Detected on 18F-NaF PET/CT.

机构信息

From the Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Parel Mumbai, India.

出版信息

Clin Nucl Med. 2016 Jun;41(6):e304-6. doi: 10.1097/RLU.0000000000001174.

DOI:10.1097/RLU.0000000000001174
PMID:26909709
Abstract

Osteosarcoma is the most common bone sarcoma in adolescents and children. Tumor thrombus arising from osteosarcoma is rare. We describe the case of a 13-year-old girl with osteosarcoma of the right femur, in whom the F-NaF PET/CT was done for initial staging to look for skeletal metastases. The scan showed abnormal increased tracer uptake in the primary tumor and the right common femoral and external iliac vein representing a tumor thrombus. Our case emphasizes the importance of extraosseous findings on F-NaF PET/CT, which may result in important management changes.

摘要

骨肉瘤是青少年和儿童中最常见的骨肉瘤。骨肉瘤引起的肿瘤血栓很少见。我们描述了一例 13 岁女孩右侧股骨骨肉瘤的病例,该患者进行 F-NaF PET/CT 初始分期以寻找骨骼转移。扫描显示原发性肿瘤和右侧股总静脉和髂外静脉异常摄取示踪剂增加,代表肿瘤血栓。我们的病例强调了 F-NaF PET/CT 上的骨外发现的重要性,这可能导致重要的治疗管理改变。

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Radiological characteristics and predisposing factors of venous tumor thrombus in pelvic osteosarcoma: A mono-institutional retrospective study of 115 cases.骨盆骨肉瘤静脉瘤栓的放射学特征及易患因素:单机构回顾性研究 115 例。
Cancer Med. 2018 Oct;7(10):4903-4913. doi: 10.1002/cam4.1739. Epub 2018 Aug 23.